Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Latesh Lad

Showing results (21-30 of 34) with videos related to

Pageof 4
Sort By:
The Journal of Biological Chemistry|January 30, 2015
Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δJohn R Somoza, David Koditek, Armando G Villaseñor, et al.
Biochemistry|March 17, 2015
Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assemblyLatesh Lad, Sheila Clancy, David Koditek, et al.
Journal of Medicinal Chemistry|January 21, 2017
Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856Stephane Perreault, Jayaraman Chandrasekhar, Zhi-Hua Cui, et al.
Journal of Medicinal Chemistry|September 24, 2016
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic StabilityLeena Patel, Jayaraman Chandrasekhar, Jerry Evarts, et al.
Nature Chemical Biology|October 9, 2007
ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanismLusong Luo, Cynthia A Parrish, Neysa Nevins, et al.
Liver International : Official Journal of the International Association for the Study of the Liver|May 21, 2026
Safety, Tolerability, and Pharmacodynamics of GS-4224 in Healthy Participants and Participants With Chronic Hepatitis BEdward J Gane, Chi-Yi Chen, Cheng-Hao Tseng, et al.
Journal of Medicinal Chemistry|March 17, 2016
2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective InhibitorsLeena Patel, Jayaraman Chandrasekhar, Jerry Evarts, et al.
Gut|January 30, 2023
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitroMarzia Rossi, Andrea Vecchi, Camilla Tiezzi, et al.
Antimicrobial Agents and Chemotherapy|June 27, 2026
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metaboliteYili Xu, Albert Liclican, Xiaofeng Zhao, et al.
Bioorganic & Medicinal Chemistry|January 5, 2019
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitorDavid Sperandio, Vangelis Aktoudianakis, Kerim Babaoglu, et al.
Pageof 4

Showing results (21-30 of 34) with videos related to

Sort By:
Pageof 4
The Journal of Biological Chemistry|January 30, 2015
Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δJohn R Somoza, David Koditek, Armando G Villaseñor, et al.
Biochemistry|March 17, 2015
Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assemblyLatesh Lad, Sheila Clancy, David Koditek, et al.
Journal of Medicinal Chemistry|January 21, 2017
Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856Stephane Perreault, Jayaraman Chandrasekhar, Zhi-Hua Cui, et al.
Journal of Medicinal Chemistry|September 24, 2016
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic StabilityLeena Patel, Jayaraman Chandrasekhar, Jerry Evarts, et al.
Nature Chemical Biology|October 9, 2007
ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanismLusong Luo, Cynthia A Parrish, Neysa Nevins, et al.
Liver International : Official Journal of the International Association for the Study of the Liver|May 21, 2026
Safety, Tolerability, and Pharmacodynamics of GS-4224 in Healthy Participants and Participants With Chronic Hepatitis BEdward J Gane, Chi-Yi Chen, Cheng-Hao Tseng, et al.
Journal of Medicinal Chemistry|March 17, 2016
2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective InhibitorsLeena Patel, Jayaraman Chandrasekhar, Jerry Evarts, et al.
Gut|January 30, 2023
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitroMarzia Rossi, Andrea Vecchi, Camilla Tiezzi, et al.
Antimicrobial Agents and Chemotherapy|June 27, 2026
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metaboliteYili Xu, Albert Liclican, Xiaofeng Zhao, et al.
Bioorganic & Medicinal Chemistry|January 5, 2019
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitorDavid Sperandio, Vangelis Aktoudianakis, Kerim Babaoglu, et al.
Pageof 4