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Journal of Medicinal Chemistry|November 17, 2015
Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of DyslipidemiaMichael J Genin, Ana B Bueno, Javier Agejas Francisco, et al.The Journal of Pharmacology and Experimental Therapeutics|August 2, 2003
A natural product ligand of the oxysterol receptor, liver X receptorKelli S Bramlett, Keith A Houck, Kristen M Borchert, et al.Journal of Lipid Research|January 18, 2006
A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activityRobert J Schmidt, James V Ficorilli, Youyan Zhang, et al.The Journal of Biological Chemistry|January 17, 2013
Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretionRebecca R Miles, William Perry, Joseph V Haas, et al.Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|August 8, 2018
Disentangling the genetic overlap between cholesterol and suicide riskEmma E M Knowles, Joanne E Curran, Peter J Meikle, et al.Circulation. Genomic and Precision Medicine|April 23, 2021
Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in ANGPTL3Nicholas B Blackburn, Peter J Meikle, Juan M Peralta, et al.Nature|May 8, 2024
Discovery of potent small-molecule inhibitors of lipoprotein(a) formationNuria Diaz, Carlos Perez, Ana Maria Escribano, et al.Plos One|January 30, 2014
Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysmsPleunie van den Borne, Sander W van der Laan, Sandra M Bovens, et al.Journal of Lipid Research|June 23, 2019
Rare DEGS1 variant significantly alters de novo ceramide synthesis pathwayNicholas B Blackburn, Laura F Michael, Peter J Meikle, et al.Scientific Reports|April 29, 2026
Unraveling the physiological impact of ANGPTL8 loss-of-function variants in humansArkan Abadi, Yan Q Chen, Shareef Khalid, et al.Pageof 3