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Genes|December 19, 2020
Distinct Effects of Inflammation on Cytochrome P450 Regulation and Drug Metabolism: Lessons from Experimental Models and a Potential Role for PharmacogeneticsLaura M de Jong, Wim Jiskoot, Jesse J Swen, et al.
British Journal of Clinical Pharmacology|April 29, 2022
A systematic review on disease-drug-drug interactions with immunomodulating drugs: A critical appraisal of risk assessment and drug labellingLaura M de Jong, Sylvia D Klomp, Nicoline Treijtel, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease|February 19, 2019
Inhibition of PRMT3 activity reduces hepatic steatosis without altering atherosclerosis susceptibility in apoE knockout miceMenno Hoekstra, Joya E Nahon, Laura M de Jong, et al.
Biomolecules|April 27, 2024
LXR Agonist T0901317's Hepatic Impact Overrules Its Atheroprotective Action in Macrophages, Driving Early Atherogenesis in Chow-Diet-Fed Male Apolipoprotein E Knockout MiceMenno Hoekstra, Laura M de Jong, Rick van der Geest, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 30, 2024
CYP P450 and non-CYP P450 Drug Metabolizing Enzyme Families Exhibit Differential Sensitivities towards Proinflammatory Cytokine ModulationLaura M de Jong, Chandan Harpal, Dirk-Jan van den Berg, et al.
Frontiers in Pharmacology|June 26, 2023
The impact of CYP2C19 genotype on phenoconversion by concomitant medicationLaura M de Jong, Soukayna Boussallami, Elena Sánchez-López, et al.
Clinical Pharmacokinetics|October 28, 2024
Changes in Plasma Clearance of CYP450 Probe Drugs May Not be Specific for Altered In Vivo Enzyme Activity Under (Patho)Physiological Conditions: How to Interpret Findings of Probe Cocktail StudiesLaura M de Jong, Marinda van de Kreeke, Mariam Ahmadi, et al.
Scientific Reports|January 11, 2022
PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout miceLaura M de Jong, Zhengzheng Zhang, Yvette den Hartog, et al.
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