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Gene Therapy|February 2, 2023
Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxisAmira D Rghei, Jacob G E Yates, Jordyn A Lopes, et al.
Molecular Therapy. Methods & Clinical Development|September 12, 2022
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challengeLaura P van Lieshout, Amira D Rghei, Wenguang Cao, et al.
Nature Communications|August 9, 2020
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiencyMartin H Kang, Laura P van Lieshout, Liqun Xu, et al.
Gene Therapy|September 1, 2022
Adeno-associated virus mediated expression of monoclonal antibody MR191 protects mice against Marburg virus and provides long-term expression in sheepAmira D Rghei, Laura P van Lieshout, Wenguang Cao, et al.
Molecular Therapy. Methods & Clinical Development|June 5, 2023
A novel dual-plasmid platform provides scalable transfection yielding improved productivity and packaging across multiple AAV serotypes and genomesLaura P van Lieshout, Miranda Rubin, Katrina Costa-Grant, et al.
Biomedicines|September 28, 2021
Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal ModelsAmira D Rghei, Laura P van Lieshout, Benjamin M McLeod, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|October 8, 2023
A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiencySylvia P Thomas, Jakob M Domm, Jacob P van Vloten, et al.
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