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Iscience|September 8, 2022
Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicityOana Hangiu, Marta Compte, Anders Dinesen, et al.The New England Journal of Medicine|December 6, 2023
Baricitinib and β-Cell Function in Patients with New-Onset Type 1 DiabetesMichaela Waibel, John M Wentworth, Michelle So, et al.Journal of Medicinal Chemistry|February 11, 2026
Identification of Compound 15 (MMV1581361) as a PfATP4 Inhibitor with Transmission-Blocking Activity and In Vivo Efficacy in a SCID Mouse Model of MalariaHenry A Onyame, Stephen Brand, Delphin Baud, et al.Oncoimmunology|April 28, 2023
A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor responseLaura Rubio-Pérez, Rodrigo Lázaro-Gorines, Seandean L Harwood, et al.The Journal of Biological Chemistry|May 1, 2004
Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activityAngus Cameron, Jon Read, Rebecca Tranter, et al.Nature Communications|November 17, 2018
A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicityMarta Compte, Seandean Lykke Harwood, Ines G Muñoz, et al.Proceedings of the National Academy of Sciences of the United States of America|August 7, 2013
Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodiesDavid Sánchez-Martín, Jorge Martínez-Torrecuadrada, Tambet Teesalu, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 31, 2021
An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without ToxicityMarta Compte, Seandean L Harwood, Ainhoa Erce-Llamazares, et al.Science Translational Medicine|June 10, 2026
The pyrrolidinamide antimalarial drug MMV367 rapidly clears blood-stage Plasmodium falciparum in healthy adults with experimental malariaBridget E Barber, Robin Denhardt-Eriksson, Etienne A Guirou, et al.Journal of Medicinal Chemistry|June 18, 2016
Trisubstituted Pyrimidines as Efficacious and Fast-Acting AntimalarialsNeil R Norcross, Beatriz Baragaña, Caroline Wilson, et al.Pageof 11