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The Journal of Pharmacology and Experimental Therapeutics|March 26, 2026
Direct protamine activation of human mast cells is MRGPRX2-dependent and is modulated by heparinNithya A Fernandopulle, Jie Ding, Gavan Francis, et al.
Molecular Pharmacology|May 26, 2007
Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptorsLauren T May, Vimesh A Avlani, Christopher J Langmead, et al.
Frontiers in Endocrinology|July 12, 2023
Small molecule allosteric modulation of the adenosine A1 receptorAnh T N Nguyen, Quan L Tran, Jo-Anne Baltos, et al.
Patterns (New York, N.Y.)|October 27, 2025
Large language models for drug discovery and developmentYizhen Zheng, Huan Yee Koh, Jiaxin Ju, et al.
Clinical and Experimental Pharmacology & Physiology|July 6, 2016
VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte modelChung H Chuo, Shane M Devine, Peter J Scammells, et al.
Neuropharmacology|February 15, 2019
Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacologyKathy Sengmany, Shane D Hellyer, Sabine Albold, et al.
Journal of Medicinal Chemistry|October 23, 2025
Structure-Activity Relationships of Highly Potent and Selective A2B Adenosine Receptor AgonistsChristopher J Smedley, Jon Kyle Awalt, Anh T N Nguyen, et al.
Biochemical Pharmacology|March 28, 2017
Capadenoson, a clinically trialed partial adenosine A1 receptor agonist, can stimulate adenosine A2B receptor biased agonismJo-Anne Baltos, Elizabeth A Vecchio, Matthew A Harris, et al.
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