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Journal of Chemical Information and Modeling
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December 11, 2012
S4MPLE--sampler for multiple protein-ligand entities: simultaneous docking of several entities
Laurent Hoffer, Dragos Horvath
Methods in Molecular Biology (Clifton, N.J.)
|
May 20, 2021
Rational Design of PDZ Domain Inhibitors: Discovery of Small Organic Compounds Targeting PDZ Domains
Laurent Hoffer, Philippe Roche, Xavier Morelli
Journal of Chemical Information and Modeling
|
March 30, 2013
In silico fragment-based drug discovery: setup and validation of a fragment-to-lead computational protocol using S4MPLE
Laurent Hoffer, Jean-Paul Renaud, Dragos Horvath
Combinatorial Chemistry & High Throughput Screening
|
April 28, 2011
Fragment-based drug design: computational & experimental state of the art
Laurent Hoffer, Jean-Paul Renaud, Dragos Horvath
Molecular Informatics
|
July 28, 2018
Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches
Laurent Hoffer, Christophe Muller, Philippe Roche, et al.
Molecules (Basel, Switzerland)
|
May 22, 2015
S4MPLE--Sampler for Multiple Protein-Ligand Entities: Methodology and Rigid-Site Docking Benchmarking
Laurent Hoffer, Camelia Chira, Gilles Marcou, et al.
Journal of Chemical Information and Modeling
|
March 26, 2019
CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy
Laurent Hoffer, Magali Saez-Ayala, Dragos Horvath, et al.
Nucleic Acids Research
|
April 30, 2024
ChemoDOTS: a web server to design chemistry-driven focused libraries
Laurent Hoffer, Guillaume Charifi-Hoareau, Sarah Barelier, et al.
European Journal of Medicinal Chemistry
|
October 28, 2018
Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors
Jessica Hernandez, Laurent Hoffer, Bruno Coutard, et al.
ACS Chemical Biology
|
April 28, 2022
Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer
Laetitia Ganier, Stephane Betzi, Carine Derviaux, et al.
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Search research articles
Search
Showing results (1-10 of 29) with videos related to
Sort By:
Page
of 3
Journal of Chemical Information and Modeling
|
December 11, 2012
S4MPLE--sampler for multiple protein-ligand entities: simultaneous docking of several entities
Laurent Hoffer, Dragos Horvath
Methods in Molecular Biology (Clifton, N.J.)
|
May 20, 2021
Rational Design of PDZ Domain Inhibitors: Discovery of Small Organic Compounds Targeting PDZ Domains
Laurent Hoffer, Philippe Roche, Xavier Morelli
Journal of Chemical Information and Modeling
|
March 30, 2013
In silico fragment-based drug discovery: setup and validation of a fragment-to-lead computational protocol using S4MPLE
Laurent Hoffer, Jean-Paul Renaud, Dragos Horvath
Combinatorial Chemistry & High Throughput Screening
|
April 28, 2011
Fragment-based drug design: computational & experimental state of the art
Laurent Hoffer, Jean-Paul Renaud, Dragos Horvath
Molecular Informatics
|
July 28, 2018
Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches
Laurent Hoffer, Christophe Muller, Philippe Roche, et al.
Molecules (Basel, Switzerland)
|
May 22, 2015
S4MPLE--Sampler for Multiple Protein-Ligand Entities: Methodology and Rigid-Site Docking Benchmarking
Laurent Hoffer, Camelia Chira, Gilles Marcou, et al.
Journal of Chemical Information and Modeling
|
March 26, 2019
CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy
Laurent Hoffer, Magali Saez-Ayala, Dragos Horvath, et al.
Nucleic Acids Research
|
April 30, 2024
ChemoDOTS: a web server to design chemistry-driven focused libraries
Laurent Hoffer, Guillaume Charifi-Hoareau, Sarah Barelier, et al.
European Journal of Medicinal Chemistry
|
October 28, 2018
Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors
Jessica Hernandez, Laurent Hoffer, Bruno Coutard, et al.
ACS Chemical Biology
|
April 28, 2022
Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer
Laetitia Ganier, Stephane Betzi, Carine Derviaux, et al.
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of 3