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Lawrence de Garavilla

Showing results (21-30 of 33) with videos related to

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Journal of Medicinal Chemistry|August 22, 2003
Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketoneMichael J Costanzo, Stephen C Yabut, Harold R Almond, et al.
Journal of the American Chemical Society|April 11, 2002
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug designMichael N Greco, Michael J Hawkins, Eugene T Powell, et al.
The Journal of Biological Chemistry|November 6, 2007
Structural basis for elastolytic substrate specificity in rodent alpha-chymasesJukka Kervinen, Marta Abad, Carl Crysler, et al.
Clinical and Experimental Pharmacology & Physiology|April 20, 2006
Characterization of RWJ-351647, a novel nonpeptide vasopressin V2 receptor antagonistJoseph W Gunnet, Jay M Matthews, Bruce E Maryanoff, et al.
Bioorganic & Medicinal Chemistry|February 24, 2006
Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agentEdward C Lawson, Rosemary J Santulli, Alexey B Dyatkin, et al.
European Journal of Pharmacology|July 5, 2008
Pharmacological characterization of RWJ-676070, a dual vasopressin V(1A)/V(2) receptor antagonistJoseph W Gunnet, Pamela Wines, Min Xiang, et al.
Bioorganic & Medicinal Chemistry Letters|March 18, 2003
Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonistsJay M Matthews, Michael N Greco, Leonard R Hecker, et al.
Journal of Medicinal Chemistry|March 17, 2007
Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymaseMichael N Greco, Michael J Hawkins, Eugene T Powell, et al.
Journal of Medicinal Chemistry|March 18, 2005
In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug designMichael J Costanzo, Harold R Almond, Leonard R Hecker, et al.
Bioorganic & Medicinal Chemistry Letters|February 15, 2008
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivativesMichael J Costanzo, Stephen C Yabut, Han-Cheng Zhang, et al.
Pageof 4

Showing results (21-30 of 33) with videos related to

Sort By:
Pageof 4
Journal of Medicinal Chemistry|August 22, 2003
Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketoneMichael J Costanzo, Stephen C Yabut, Harold R Almond, et al.
Journal of the American Chemical Society|April 11, 2002
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug designMichael N Greco, Michael J Hawkins, Eugene T Powell, et al.
The Journal of Biological Chemistry|November 6, 2007
Structural basis for elastolytic substrate specificity in rodent alpha-chymasesJukka Kervinen, Marta Abad, Carl Crysler, et al.
Clinical and Experimental Pharmacology & Physiology|April 20, 2006
Characterization of RWJ-351647, a novel nonpeptide vasopressin V2 receptor antagonistJoseph W Gunnet, Jay M Matthews, Bruce E Maryanoff, et al.
Bioorganic & Medicinal Chemistry|February 24, 2006
Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agentEdward C Lawson, Rosemary J Santulli, Alexey B Dyatkin, et al.
European Journal of Pharmacology|July 5, 2008
Pharmacological characterization of RWJ-676070, a dual vasopressin V(1A)/V(2) receptor antagonistJoseph W Gunnet, Pamela Wines, Min Xiang, et al.
Bioorganic & Medicinal Chemistry Letters|March 18, 2003
Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonistsJay M Matthews, Michael N Greco, Leonard R Hecker, et al.
Journal of Medicinal Chemistry|March 17, 2007
Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymaseMichael N Greco, Michael J Hawkins, Eugene T Powell, et al.
Journal of Medicinal Chemistry|March 18, 2005
In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug designMichael J Costanzo, Harold R Almond, Leonard R Hecker, et al.
Bioorganic & Medicinal Chemistry Letters|February 15, 2008
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivativesMichael J Costanzo, Stephen C Yabut, Han-Cheng Zhang, et al.
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