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ACS Chemical Biology|November 16, 2020
Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction StabilizersEline Sijbesma, Bente A Somsen, Galen P Miley, et al.
Journal of the American Chemical Society|March 17, 2023
Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein-Protein Interaction as a Molecular Glue Drug Discovery ApproachBente A Somsen, Rick J C Schellekens, Carlo J A Verhoef, et al.
The Journal of Biological Chemistry|May 24, 2023
Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complexBente A Somsen, Eline Sijbesma, Seppe Leysen, et al.
ACS Synthetic Biology|August 21, 2018
Protease-Activatable Scaffold Proteins as Versatile Molecular Hubs in Synthetic Signaling NetworksStijn J A Aper, Anniek den Hamer, Simone F A Wouters, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|May 25, 2012
Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivoCarolin Bier, Shirley K Knauer, Désirée Wünsch, et al.
The Biochemical Journal|February 11, 2010
Electrostatic interactions play a minor role in the binding of ExoS to 14-3-3 proteinsLubna Yasmin, Jeffrey L Veesenmeyer, Maureen H Diaz, et al.
Translational Oncology|August 2, 2011
The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivoChristina Schönherr, Kristina Ruuth, Therese Eriksson, et al.
Journal of Medicinal Chemistry|October 14, 2017
Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein-Protein InteractionsDennis M Krüger, Adrian Glas, David Bier, et al.
Angewandte Chemie (International Ed. in English)|August 21, 2020
Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based TetheringMadita Wolter, Dario Valenti, Peter J Cossar, et al.
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