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Science Signaling|September 3, 2020
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholambanJulia Menzel, Daniel Kownatzki-Danger, Sergiy Tokar, et al.ACS Chemical Biology|November 20, 2019
Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σAve Kuusk, João Filipe Neves, Kenny Bravo-Rodriguez, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|June 25, 2015
Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by TauYuyoung Joo, Benjamin Schumacher, Isabelle Landrieu, et al.Nature Communications|June 23, 2022
Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTRLoes M Stevers, Madita Wolter, Graeme W Carlile, et al.Angewandte Chemie (International Ed. in English)|July 16, 2023
From Tethered to Freestanding Stabilizers of 14-3-3 Protein-Protein Interactions through Fragment LinkingEmira J Visser, Priyadarshini Jaishankar, Eline Sijbesma, et al.Biochemistry|August 22, 2024
Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein InteractionBlaž Andlovic, Dario Valenti, Federica Centorrino, et al.Nature Communications|July 15, 2026
Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTACCarlo J A Verhoef, Charlotte Crowe, Mark A Nakasone, et al.Journal of Medicinal Chemistry|May 19, 2021
Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γtFemke A Meijer, Annet O W M Saris, Richard G Doveston, et al.Cell Chemical Biology|May 2, 2023
IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilizationBlaž Andlovic, Geronimo Heilmann, Sabrina Ninck, et al.Journal of Medicinal Chemistry|October 3, 2017
Modulators of 14-3-3 Protein-Protein InteractionsLoes M Stevers, Eline Sijbesma, Maurizio Botta, et al.Pageof 20