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Communications Chemistry|March 23, 2025
Structural insight into the cGAS active site explains differences between therapeutically relevant speciesAlexander M Skeldon, Li Wang, Nicolas Sgarioto, et al.Bioorganic & Medicinal Chemistry Letters|November 20, 2010
Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assemblyLee D Fader, Richard Bethell, Pierre Bonneau, et al.Antimicrobial Agents and Chemotherapy|March 26, 2014
Preclinical profile of BI 224436, a novel HIV-1 non-catalytic-site integrase inhibitorCraig Fenwick, Ma'an Amad, Murray D Bailey, et al.Molecular Cancer Therapeutics|December 16, 2021
RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP InhibitorsAnne Roulston, Michal Zimmermann, Robert Papp, et al.ACS Medicinal Chemistry Letters|August 27, 2016
Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIsLee D Fader, Murray Bailey, Eric Beaulieu, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1Lee D Fader, Eric Malenfant, Mathieu Parisien, et al.Journal of Medicinal Chemistry|February 1, 2024
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)W Cameron Black, Abbas Abdoli, Xiuli An, et al.Pageof 2