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The EMBO Journal|April 25, 2015
Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitroHolger A Russ, Audrey V Parent, Jennifer J Ringler, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 6, 2020
Evolution of insulin at the edge of foldability and its medical implicationsNischay K Rege, Ming Liu, Yanwu Yang, et al.
Diabetes|May 5, 2021
Altered β-Cell Prohormone Processing and Secretion in Type 1 DiabetesTeresa Rodriguez-Calvo, Yi-Chun Chen, C Bruce Verchere, et al.
Translational Research : the Journal of Laboratory and Clinical Medicine|August 24, 2019
Abnormalities in proinsulin processing in islets from individuals with longstanding T1DEmily K Sims, Farooq Syed, Julius Nyalwidhe, et al.
The Journal of Biological Chemistry|February 2, 2020
"Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolutionNischay K Rege, Ming Liu, Balamurugan Dhayalan, et al.
Epilepsia|September 27, 2018
Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsyJohanna Hynynen, Tytti Pokka, Jonna Komulainen-Ebrahim, et al.
JCI Insight|February 2, 2021
Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft sizeLina Sui, Yurong Xin, Qian Du, et al.
Diabetes|March 7, 2020
Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of YouthJinhong Sun, Yi Xiong, Xin Li, et al.
Diabetes|January 24, 2019
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin HandlingSeyed Mojtaba Ghiasi, Tina Dahlby, Caroline Hede Andersen, et al.
Protein Science : a Publication of the Protein Society|March 21, 2024
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasisAnoop Arunagiri, Maroof Alam, Leena Haataja, et al.
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