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The FEBS Journal|February 3, 2024
Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signalingYa-Jun Liu, Jian-Yang Wang, Xiang-Le Zhang, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|April 1, 2011
Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processingMei-Xia Che, Ya-Jun Jiang, Yuan-Yuan Xie, et al.
The Journal of Biological Chemistry|July 22, 2015
Aggregation of Polyglutamine-expanded Ataxin 7 Protein Specifically Sequesters Ubiquitin-specific Protease 22 and Deteriorates Its Deubiquitinating Function in the Spt-Ada-Gcn5-Acetyltransferase (SAGA) ComplexHui Yang, Shuai Liu, Wen-Tian He, et al.
Journal of the American Chemical Society|February 1, 2020
Solid-State NMR Reveals the Structural Transformation of the TDP-43 Amyloidogenic Region upon FibrillationXiao-Feng Zhuo, Jian Wang, Jing Zhang, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 7, 2018
PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitinHui Yang, Hong-Wei Yue, Wen-Tian He, et al.
The Biochemical Journal|October 23, 2020
Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregationWei Xue, Shu-Xian Zhang, Wen-Tian He, et al.
The Journal of Biological Chemistry|May 29, 2024
PolyQ-expanded ataxin-2 aggregation impairs cellular processing-body homeostasis via sequestering the RNA helicase DDX6Jian-Yang Wang, Ya-Jun Liu, Xiang-Le Zhang, et al.
Scientific Reports|April 1, 2016
Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formationLei-Lei Jiang, Jian Zhao, Xiao-Fang Yin, et al.
Scientific Reports|November 3, 2017
HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19Wen-Tian He, Wei Xue, Yong-Guang Gao, et al.
Acta Biochimica Et Biophysica Sinica|May 12, 2023
Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasisJun-Ye Hong, Jian-Yang Wang, Hong-Wei Yue, et al.
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