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STAR Protocols|August 10, 2024
Protocol for the isolation and purification of endoplasmic reticulum-plasma membrane junctions from the mouse brainJason A Weesner, Diantha van de Vlekkert, Leigh Ellen Fremuth, et al.Cell Reports|January 16, 2025
Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylationLeigh Ellen Fremuth, Huimin Hu, Diantha van de Vlekkert, et al.Biorxiv : the Preprint Server for Biology|July 14, 2025
Targeting Lysosomal Dysfunction to Alleviate Plaque Deposition in an Alzheimer Disease ModelLeigh Ellen Fremuth, Diantha van de Vlekkert, Huimin Hu, et al.Biorxiv : the Preprint Server for Biology|June 3, 2024
Neuraminidase 1 regulates the cellular state of microglia by modulating the sialylation of Trem2Leigh Ellen Fremuth, Huimin Hu, Diantha van de Vlekkert, et al.Cell Reports|July 25, 2026
Sex differences in somatosensory circuitry are programmed by developmental microglia-astrocyte interactionAbigayle Duffy, Leigh Ellen Fremuth, Madison Doceti, et al.Cells|August 26, 2022
Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-GangliosidosisJason Andrew Weesner, Ida Annunziata, Tianhong Yang, et al.Iscience|July 23, 2026
Microglia and its P2RY12 receptors regulate seizure severityLeigh Ellen Fremuth, Synphane Gibbs-Shelton, Madison Doceti, et al.Nature Communications|August 11, 2019
MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostatIda Annunziata, Diantha van de Vlekkert, Elmar Wolf, et al.Pageof 1