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Nature Communications|May 25, 2017
An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humansAbbey D Zuehlke, Michael Reidy, Coney Lin, et al.
Nature Structural & Molecular Biology|October 20, 2009
Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domainShinji Tsutsumi, Mehdi Mollapour, Christian Graf, et al.
Methods in Molecular Biology (Clifton, N.J.)|November 28, 2017
Detecting Posttranslational Modifications of Hsp90Rebecca A Sager, Mark R Woodford, Len Neckers, et al.
Molecular and Cellular Biology|October 13, 2006
Loss of Hsp90 association up-regulates Src-dependent ErbB2 activityWanping Xu, Xitong Yuan, Kristin Beebe, et al.
The Journal of Biological Chemistry|January 1, 2014
Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complexYuanzhong Wang, Wanping Xu, Dujin Zhou, et al.
The Journal of Urology|August 21, 2007
Intratumor injection of the Hsp90 inhibitor 17AAG decreases tumor growth and induces apoptosis in a prostate cancer xenograft modelChristopher R Williams, Ray Tabios, W Marston Linehan, et al.
Cell Cycle (Georgetown, Tex.)|September 5, 2008
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibitionItai Pashtan, Shinji Tsutsumi, Suiquan Wang, et al.
Expert Opinion on Therapeutic Targets|April 2, 2019
Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progressToshiki Kijima, Thomas Prince, Len Neckers, et al.
Cell Cycle (Georgetown, Tex.)|June 9, 2009
Cancer cells harboring MET gene amplification activate alternative signaling pathways to escape MET inhibition but remain sensitive to Hsp90 inhibitorsSuiquan Wang, Itai Pashtan, Shinji Tsutsumi, et al.
Nature Clinical Practice. Urology|February 9, 2007
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancerSunil Sudarshan, Peter A Pinto, Len Neckers, et al.
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