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Len Neckers

Showing results (141-150 of 168) with videos related to

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Cancer Cell|August 16, 2005
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stabilityJennifer S Isaacs, Yun Jin Jung, David R Mole, et al.
Nature Cell Biology|May 18, 2004
Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasivenessBrenda K Eustace, Takashi Sakurai, Jean K Stewart, et al.
BMC Biology|January 29, 2020
The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasisAbhinav Joshi, Li Dai, Yanxin Liu, et al.
Journal of Experimental & Clinical Cancer Research : CR|June 26, 2022
Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell CarcinomaRoma Pahwa, Janhavi Dubhashi, Anand Singh, et al.
Nature Communications|May 25, 2017
An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humansAbbey D Zuehlke, Michael Reidy, Coney Lin, et al.
Nature Structural & Molecular Biology|October 20, 2009
Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domainShinji Tsutsumi, Mehdi Mollapour, Christian Graf, et al.
Molecular and Cellular Biology|May 28, 2009
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen speciesSunil Sudarshan, Carole Sourbier, Hye-Sik Kong, et al.
Scientific Reports|December 6, 2019
Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-MycCarole Sourbier, Christopher J Ricketts, Pei-Jyun Liao, et al.
Immunity|June 14, 2008
The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradationAvital Lev, Kazuyo Takeda, Damien Zanker, et al.
Plos One|March 6, 2008
Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential targetMariëlle I Gallegos Ruiz, Karijn Floor, Paul Roepman, et al.
Pageof 17

Showing results (141-150 of 168) with videos related to

Sort By:
Pageof 17
Cancer Cell|August 16, 2005
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stabilityJennifer S Isaacs, Yun Jin Jung, David R Mole, et al.
Nature Cell Biology|May 18, 2004
Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasivenessBrenda K Eustace, Takashi Sakurai, Jean K Stewart, et al.
BMC Biology|January 29, 2020
The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasisAbhinav Joshi, Li Dai, Yanxin Liu, et al.
Journal of Experimental & Clinical Cancer Research : CR|June 26, 2022
Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell CarcinomaRoma Pahwa, Janhavi Dubhashi, Anand Singh, et al.
Nature Communications|May 25, 2017
An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humansAbbey D Zuehlke, Michael Reidy, Coney Lin, et al.
Nature Structural & Molecular Biology|October 20, 2009
Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domainShinji Tsutsumi, Mehdi Mollapour, Christian Graf, et al.
Molecular and Cellular Biology|May 28, 2009
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen speciesSunil Sudarshan, Carole Sourbier, Hye-Sik Kong, et al.
Scientific Reports|December 6, 2019
Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-MycCarole Sourbier, Christopher J Ricketts, Pei-Jyun Liao, et al.
Immunity|June 14, 2008
The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradationAvital Lev, Kazuyo Takeda, Damien Zanker, et al.
Plos One|March 6, 2008
Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential targetMariëlle I Gallegos Ruiz, Karijn Floor, Paul Roepman, et al.
Pageof 17