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Len Neckers

Showing results (71-80 of 168) with videos related to

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Molecular Cancer Research : MCR|September 13, 2006
Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcadeEdward G Mimnaugh, Wanping Xu, Michele Vos, et al.
The Journal of Biological Chemistry|December 19, 2002
Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha proteinYun-Jin Jung, Jennifer S Isaacs, Sunmin Lee, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 20, 2002
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/NeuWanping Xu, Monica Marcu, Xitong Yuan, et al.
Leukemia Research|October 24, 2007
KIT regulates tyrosine phosphorylation and nuclear localization of beta-catenin in mast cell leukemiaTomohiro Kajiguchi, Sunmin Lee, Min-Jung Lee, et al.
Molecular Cancer Therapeutics|February 18, 2003
17AAG: low target binding affinity and potent cell activity--finding an explanationGabriela Chiosis, Henri Huezo, Neal Rosen, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|September 6, 2003
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesisYun-Jin Jung, Jennifer S Isaacs, Sunmin Lee, et al.
Nature Structural & Molecular Biology|January 12, 2005
Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complexWanping Xu, Xitong Yuan, Zhexin Xiang, et al.
Molecular and Cellular Biology|November 26, 2002
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alphaMonica G Marcu, Melissa Doyle, Anne Bertolotti, et al.
Cell Stress & Chaperones|February 3, 2018
Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical developmentLen Neckers, Brian Blagg, Timothy Haystead, et al.
Methods in Molecular Biology (Clifton, N.J.)|August 4, 2023
Detecting Posttranslational Modifications of Hsp90 IsoformsRebecca A Sager, Sarah J Backe, Len Neckers, et al.
Pageof 17

Showing results (71-80 of 168) with videos related to

Sort By:
Pageof 17
Molecular Cancer Research : MCR|September 13, 2006
Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcadeEdward G Mimnaugh, Wanping Xu, Michele Vos, et al.
The Journal of Biological Chemistry|December 19, 2002
Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha proteinYun-Jin Jung, Jennifer S Isaacs, Sunmin Lee, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 20, 2002
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/NeuWanping Xu, Monica Marcu, Xitong Yuan, et al.
Leukemia Research|October 24, 2007
KIT regulates tyrosine phosphorylation and nuclear localization of beta-catenin in mast cell leukemiaTomohiro Kajiguchi, Sunmin Lee, Min-Jung Lee, et al.
Molecular Cancer Therapeutics|February 18, 2003
17AAG: low target binding affinity and potent cell activity--finding an explanationGabriela Chiosis, Henri Huezo, Neal Rosen, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|September 6, 2003
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesisYun-Jin Jung, Jennifer S Isaacs, Sunmin Lee, et al.
Nature Structural & Molecular Biology|January 12, 2005
Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complexWanping Xu, Xitong Yuan, Zhexin Xiang, et al.
Molecular and Cellular Biology|November 26, 2002
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alphaMonica G Marcu, Melissa Doyle, Anne Bertolotti, et al.
Cell Stress & Chaperones|February 3, 2018
Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical developmentLen Neckers, Brian Blagg, Timothy Haystead, et al.
Methods in Molecular Biology (Clifton, N.J.)|August 4, 2023
Detecting Posttranslational Modifications of Hsp90 IsoformsRebecca A Sager, Sarah J Backe, Len Neckers, et al.
Pageof 17