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Lennart Bunch

Showing results (31-40 of 70) with videos related to

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ACS Chemical Neuroscience|February 19, 2020
A Diversity Oriented Synthesis Approach to New 2,3-<i>trans</i>-Substituted l-Proline Analogs as Potential Ligands for the Ionotropic Glutamate ReceptorsSilke Kayser, Piero Temperini, Christian B M Poulie, et al.
Bioorganic & Medicinal Chemistry|October 18, 2012
Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102Tri H V Huynh, Bjarke Abrahamsen, Karsten K Madsen, et al.
Journal of Medicinal Chemistry|May 19, 2012
Structure-activity relationship study of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101) and absolute configurational assignment using infrared and vibrational circular dichroism spectroscopy in combination with ab initio Hartree-Fock calculationsTri H V Huynh, Irene Shim, Henrik Bohr, et al.
The Journal of Organic Chemistry|February 15, 2003
Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogueLennart Bunch, Tommy Liljefors, Jeremy R Greenwood, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 18, 2013
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domainBjarke Abrahamsen, Nicole Schneider, Mette N Erichsen, et al.
Journal of Medicinal Chemistry|December 13, 2005
Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3Sebastien Alaux, Mie Kusk, Emanuelle Sagot, et al.
Chemmedchem|September 5, 2009
4,4-Dimethyl- and diastereomeric 4-hydroxy-4-methyl- (2S)-glutamate analogues display distinct pharmacological profiles at ionotropic glutamate receptors and excitatory amino acid transportersLennart Bunch, Darryl S Pickering, Thierry Gefflaut, et al.
Chemmedchem|November 15, 2008
Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptorsMangaleswaran Sivaprakasam, Kasper B Hansen, Olivier David, et al.
European Journal of Medicinal Chemistry|January 21, 2024
Synthesis and pharmacological characterization of conformationally restricted 2-amino-Adipic acid analogs and carboxycyclopropyl glycines as selective metabotropic glutamate 2 receptor agonistsMarkus Staudt, Na Liu, Fanny Malhaire, et al.
Organic & Biomolecular Chemistry|October 22, 2005
Azetidinic amino acids: stereocontrolled synthesis and pharmacological characterization as ligands for glutamate receptors and transportersHans Bräuner-Osborne, Lennart Bunch, Nathalie Chopin, et al.
Pageof 7

Showing results (31-40 of 70) with videos related to

Sort By:
Pageof 7
ACS Chemical Neuroscience|February 19, 2020
A Diversity Oriented Synthesis Approach to New 2,3-<i>trans</i>-Substituted l-Proline Analogs as Potential Ligands for the Ionotropic Glutamate ReceptorsSilke Kayser, Piero Temperini, Christian B M Poulie, et al.
Bioorganic & Medicinal Chemistry|October 18, 2012
Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102Tri H V Huynh, Bjarke Abrahamsen, Karsten K Madsen, et al.
Journal of Medicinal Chemistry|May 19, 2012
Structure-activity relationship study of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101) and absolute configurational assignment using infrared and vibrational circular dichroism spectroscopy in combination with ab initio Hartree-Fock calculationsTri H V Huynh, Irene Shim, Henrik Bohr, et al.
The Journal of Organic Chemistry|February 15, 2003
Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogueLennart Bunch, Tommy Liljefors, Jeremy R Greenwood, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 18, 2013
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domainBjarke Abrahamsen, Nicole Schneider, Mette N Erichsen, et al.
Journal of Medicinal Chemistry|December 13, 2005
Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3Sebastien Alaux, Mie Kusk, Emanuelle Sagot, et al.
Chemmedchem|September 5, 2009
4,4-Dimethyl- and diastereomeric 4-hydroxy-4-methyl- (2S)-glutamate analogues display distinct pharmacological profiles at ionotropic glutamate receptors and excitatory amino acid transportersLennart Bunch, Darryl S Pickering, Thierry Gefflaut, et al.
Chemmedchem|November 15, 2008
Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptorsMangaleswaran Sivaprakasam, Kasper B Hansen, Olivier David, et al.
European Journal of Medicinal Chemistry|January 21, 2024
Synthesis and pharmacological characterization of conformationally restricted 2-amino-Adipic acid analogs and carboxycyclopropyl glycines as selective metabotropic glutamate 2 receptor agonistsMarkus Staudt, Na Liu, Fanny Malhaire, et al.
Organic & Biomolecular Chemistry|October 22, 2005
Azetidinic amino acids: stereocontrolled synthesis and pharmacological characterization as ligands for glutamate receptors and transportersHans Bräuner-Osborne, Lennart Bunch, Nathalie Chopin, et al.
Pageof 7