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Biophysical Journal|February 27, 2022
Altered cyclic nucleotide binding and pore opening in a diseased human HCN4 channelLeo C T Ng, Yue Xian Li, Filip Van Petegem, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 19, 2019
Opening TRPP2 (PKD2L1) requires the transfer of gating chargesLeo C T Ng, Thuy N Vien, Vladimir Yarov-Yarovoy, et al.
Cellular Signalling|April 7, 2020
Structure and function of polycystin channels in primary ciliaChau My Ta, Thuy N Vien, Leo C T Ng, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 26, 2020
Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domainThuy N Vien, Jinliang Wang, Leo C T Ng, et al.
Structure (London, England : 1993)|August 30, 2016
Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and OpeningLeo C T Ng, Igor Putrenko, Victoria Baronas, et al.
The Journal of General Physiology|September 5, 2019
Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide-gated ion channelLeo C T Ng, Meiying Zhuang, Filip Van Petegem, et al.
Communications Biology|February 4, 2026
An inter-subunit path is required for entropically-driven and negatively cooperative binding of cyclic nucleotides in the HCN2 channelFlavio Costa, Leo C T Ng, Sarah S Chow, et al.
Molecular Cell|January 27, 2021
A tamoxifen receptor within a voltage-gated sodium channelAltin Sula, David Hollingworth, Leo C T Ng, et al.
Nature Communications|February 17, 2017
The complete structure of an activated open sodium channelAltin Sula, Jennifer Booker, Leo C T Ng, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 12, 2019
Valproic acid interactions with the NavMs voltage-gated sodium channelGeancarlo Zanatta, Altin Sula, Andrew J Miles, et al.
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