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Chemical Research in Toxicology|November 19, 2014
Covalent adduct formation between the antihypertensive drug hydralazine and abasic sites in double- and single-stranded DNADouglas Melton, Calvin D Lewis, Nathan E Price, et al.ACS Chemical Biology|January 3, 2015
Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7A1Min Luo, Kent S Gates, Michael T Henzl, et al.Acta Crystallographica. Section E, Crystallographic Communications|August 18, 2015
Crystal structure of methyl (S)-2-{(R)-4-[(tert-but-oxy-carbon-yl)amino]-3-oxo-1,2-thia-zolidin-2-yl}-3-methyl-butano-ate: a chemical model for oxidized protein tyrosine phosphatase 1B (PTP1B)Kasi Viswanatharaju Ruddraraju, Roman Hillebrand, Charles L Barnes, et al.Biochemistry|June 25, 2015
Characterization of Interstrand DNA-DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ29 DNA PolymeraseZhiyu Yang, Nathan E Price, Kevin M Johnson, et al.Bioorganic & Medicinal Chemistry Letters|July 4, 2008
Oxidative inactivation of protein tyrosine phosphatase 1B by organic hydroperoxidesSanjib Bhattacharya, Jason N Labutti, Derrick R Seiner, et al.Journal of the American Chemical Society|October 27, 2005
DNA damage by fasicularinSanjay Dutta, Hideki Abe, Sakae Aoyagi, et al.Bioorganic & Medicinal Chemistry|May 3, 2016
Sulfone-stabilized carbanions for the reversible covalent capture of a posttranslationally-generated cysteine oxoform found in protein tyrosine phosphatase 1B (PTP1B)Zachary D Parsons, Kasi Viswanatharaju Ruddraraju, Nicholas Santo, et al.RSC Advances|May 9, 2022
Selective covalent capture of a DNA sequence corresponding to a cancer-driving C>G mutation in the KRAS gene by a chemically reactive probe: optimizing a cross-linking reaction with non-canonical duplex structuresXu Guo, Maryam Imani Nejad, Li-Qun Gu, et al.Acta Crystallographica. Section E, Crystallographic Communications|June 2, 2015
Crystal structure of 5-{4'-[(2-{2-[2-(2-ammonio-eth-oxy)eth-oxy]eth-oxy}eth-yl)carbamo-yl]-4-meth-oxy-[1,1'-biphen-yl]-3-yl}-3-oxo-1,2,5-thia-diazo-lidin-2-ide 1,1-dioxide: a potential inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B)Kasi Viswanatharaju Ruddraraju, Roman Hillebrand, Charles L Barnes, et al.Chemical Research in Toxicology|January 5, 2024
Formation and Properties of DNA Adducts Generated by Reactions of Abasic Sites with 1,2-Aminothiols Including Cysteamine, Cysteine Methyl Ester, and Peptides Containing N-Terminal Cysteine ResiduesAnuoluwapo Gomina, Tanhaul Islam, Garam Shim, et al.Pageof 18