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Molecular Pharmacology|January 8, 2017
Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor SignalingAndrew T Bender, Anna Gardberg, Albertina Pereira, et al.Journal of Immunology (Baltimore, Md. : 1950)|April 17, 2019
Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease ModelsPhilipp Haselmayer, Montserrat Camps, Lesley Liu-Bujalski, et al.Bioorganic & Medicinal Chemistry Letters|October 7, 2018
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of BtkRichard Caldwell, Lesley Liu-Bujalski, Hui Qiu, et al.Bioorganic & Medicinal Chemistry Letters|August 21, 2018
Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hitHui Qiu, Lesley Liu-Bujalski, Richard D Caldwell, et al.Chemmedchem|December 7, 2018
Discovery of Affinity-Based Probes for Btk Occupancy AssaysHui Qiu, Richard Caldwell, Lesley Liu-Bujalski, et al.Clinical Immunology (Orlando, Fla.)|January 29, 2016
Btk inhibition treats TLR7/IFN driven murine lupusAndrew T Bender, Albertina Pereira, Kai Fu, et al.Bioorganic & Medicinal Chemistry Letters|September 24, 2018
Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitorsHui Qiu, Lesley Liu-Bujalski, Richard D Caldwell, et al.ACS Medicinal Chemistry Letters|May 17, 2023
Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with MyelosuppressionSatenig Guler, Maria C DiPoto, Alejandro Crespo, et al.Bioorganic & Medicinal Chemistry Letters|April 11, 2013
SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitorsSrinivasa Karra, Yufang Xiao, Xiaoling Chen, et al.Journal of Medicinal Chemistry|August 2, 2019
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological DiseasesRichard D Caldwell, Hui Qiu, Ben C Askew, et al.Pageof 1