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EMBO Molecular Medicine|May 6, 2022
Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemiaJoan So, Alexander C Lewis, Lorey K Smith, et al.
Cell Reports|August 17, 2022
Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cellsEmily Gruber, Joan So, Alexander C Lewis, et al.
Nature|December 9, 2021
Non-genetic determinants of malignant clonal fitness at single-cell resolutionKatie A Fennell, Dane Vassiliadis, Enid Y N Lam, et al.
Nature Communications|May 29, 2021
CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacyLauren Giuffrida, Kevin Sek, Melissa A Henderson, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|August 1, 2020
IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid TumorsLauren Giuffrida, Kevin Sek, Melissa A Henderson, et al.
Molecular Cancer Therapeutics|November 4, 2025
Discovery and characterisation of VPRBP/DCAF1 kinase inhibitor analogues as microtubular destabilising agents with potent anti-myeloma activityOlivia Susanto, Emily Gruber, Cheng Mun Wun, et al.
Immunity|April 16, 2021
Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell developmentLuyi Tian, Sara Tomei, Jaring Schreuder, et al.
Leukemia|April 23, 2022
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphomaJonathan Wong, Emily Gruber, Belinda Maher, et al.
Cell|November 20, 2025
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemiaAlexander C Lewis, Emily Gruber, Rheana Franich, et al.
Cancer Discovery|March 21, 2022
Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AMLJessica M Salmon, Izabela Todorovski, Kym L Stanley, et al.
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