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Genes & Diseases|February 12, 2020
Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapiesHongxing Shen, Eddy Shih-Hsin Yang, Marty Conry, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 7, 2013
Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cellsLewis Zhichang Shi, Nishan S Kalupahana, Meghan E Turnis, et al.
Research Square|January 23, 2024
HIF1α-glycolysis engages activation-induced cell death to drive IFN-γ induction in hypoxic T cellsHongxing Shen, Logan Mullen, Oluwagbemiga A Ojo, et al.
Nature Communications|August 9, 2016
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapyLewis Zhichang Shi, Tihui Fu, Baoxiang Guan, et al.
Immunity|December 27, 2011
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activationRuoning Wang, Christopher P Dillon, Lewis Zhichang Shi, et al.
Cancer Immunology Research|August 31, 2019
Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated MannerLewis Zhichang Shi, Sangeeta Goswami, Tihui Fu, et al.
Nature Communications|August 25, 2022
Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signalingHongxing Shen, Fengyuan Huang, Xiangmin Zhang, et al.
Nature Communications|October 31, 2024
HIF1α-regulated glycolysis promotes activation-induced cell death and IFN-γ induction in hypoxic T cellsHongxing Shen, Oluwagbemiga A Ojo, Haitao Ding, et al.
Cell|September 27, 2016
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 TherapyJianjun Gao, Lewis Zhichang Shi, Hao Zhao, et al.
Frontiers in Cell and Developmental Biology|October 10, 2022
B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functionsDiaoyi Tan, Wei Yin, Fei Guan, et al.
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