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Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 3, 2020
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment
Simon G Wong, Diane Ramsden, Shannon Dallas, et al.
Nucleic Acids Research
|
November 8, 2014
APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals
Leiming You, Jiexin Wu, Yuchao Feng, et al.
Mutagenesis
|
January 6, 2024
N-Nitrosodimethylamine investigations in Muta™Mouse define point-of-departure values and demonstrate less-than-additive somatic mutant frequency accumulations
Anthony M Lynch, Jonathan Howe, Deon Hildebrand, et al.
Chemical Research in Toxicology
|
August 31, 2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds
Melanie Z Sakatis, Melinda J Reese, Andrew W Harrell, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 1, 2018
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance
Jane R Kenny, Diane Ramsden, David B Buckley, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
February 9, 2019
Immuno-PET Imaging to Assess Target Engagement: Experience from <sup>89</sup>Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors
C Willemien Menke-van der Houven van Oordt, Adam McGeoch, Mats Bergstrom, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 25, 2017
Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control
Niresh Hariparsad, Diane Ramsden, Jairam Palamanda, et al.
Science China. Life Sciences
|
May 29, 2024
Disruption of PABPN1 phase separation by SNRPD2 drives colorectal cancer cell proliferation and migration through promoting alternative polyadenylation of CTNNBIP1
Zhijie Hu, Mengxia Li, Yufeng Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
May 24, 2014
Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins
Laurent Salphati, Xiaoyan Chu, Liangfu Chen, et al.
Molecular Pharmacology
|
February 20, 2016
Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model
Shannon Dallas, Laurent Salphati, David Gomez-Zepeda, et al.
Page
of 6
Search research articles
Search
Showing results (41-50 of 51) with videos related to
Sort By:
Page
of 6
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 3, 2020
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment
Simon G Wong, Diane Ramsden, Shannon Dallas, et al.
Nucleic Acids Research
|
November 8, 2014
APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals
Leiming You, Jiexin Wu, Yuchao Feng, et al.
Mutagenesis
|
January 6, 2024
N-Nitrosodimethylamine investigations in Muta™Mouse define point-of-departure values and demonstrate less-than-additive somatic mutant frequency accumulations
Anthony M Lynch, Jonathan Howe, Deon Hildebrand, et al.
Chemical Research in Toxicology
|
August 31, 2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds
Melanie Z Sakatis, Melinda J Reese, Andrew W Harrell, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 1, 2018
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance
Jane R Kenny, Diane Ramsden, David B Buckley, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
February 9, 2019
Immuno-PET Imaging to Assess Target Engagement: Experience from <sup>89</sup>Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors
C Willemien Menke-van der Houven van Oordt, Adam McGeoch, Mats Bergstrom, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 25, 2017
Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control
Niresh Hariparsad, Diane Ramsden, Jairam Palamanda, et al.
Science China. Life Sciences
|
May 29, 2024
Disruption of PABPN1 phase separation by SNRPD2 drives colorectal cancer cell proliferation and migration through promoting alternative polyadenylation of CTNNBIP1
Zhijie Hu, Mengxia Li, Yufeng Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
May 24, 2014
Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins
Laurent Salphati, Xiaoyan Chu, Liangfu Chen, et al.
Molecular Pharmacology
|
February 20, 2016
Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model
Shannon Dallas, Laurent Salphati, David Gomez-Zepeda, et al.
Page
of 6