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ACS Medicinal Chemistry Letters|November 20, 2020
Discovery of SHR0687, a Highly Potent and Peripheral Nervous System-Restricted KOR AgonistXin Li, Hong Wan, Ping Dong, et al.
Proteins|May 6, 2022
Comprehensive folding variations for protein foldingJiaan Yang, Wen Xiang Cheng, Xiao Fei Zhao, et al.
Molecular Cancer Therapeutics|April 10, 2019
Discovery of A Novel EGFR-Targeting Antibody-Drug Conjugate, SHR-A1307, for the Treatment of Solid Tumors Resistant or Refractory to Anti-EGFR TherapiesKaijie He, Jianyan Xu, Jindong Liang, et al.
Bioorganic & Medicinal Chemistry|January 11, 2018
Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffoldBiao Lu, Song Huang, Jingsong Cao, et al.
ACS Omega|August 29, 2019
Discovery of SHR9352: A Highly Potent G Protein-Biased μ-Opioid Receptor AgonistXin Li, Wei He, Yang Chen, et al.
Cellular Signalling|June 22, 2025
LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney diseaseZhibin Fan, Yue Zhang, Liming Yuan, et al.
Angewandte Chemie (International Ed. in English)|November 25, 2024
Allosteric CDC37 Inhibitor Disrupts Chaperone Complex to Block CDK4/6 MaturationLixiao Zhang, Wei Liu, Zhen Zheng, et al.
ACS Medicinal Chemistry Letters|June 22, 2019
Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase InhibitorsWangyang Tu, Fanglong Yang, Guoji Xu, et al.
Scientific Reports|April 29, 2021
Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasisSuxing Liu, Dong Liu, Ru Shen, et al.
Bioorganic & Medicinal Chemistry Letters|July 6, 2016
WITHDRAWN: Discovery of SHR1977: A highly potent and selective ROMK inhibitorXin Li, Yun Zhang, Yang Chen, et al.
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