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Bioorganic & Medicinal Chemistry Letters|September 10, 2011
Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitorJohn Liddle, Francis L Atkinson, Michael D Barker, et al.
Journal of Medicinal Chemistry|June 22, 2026
Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity <i>In Vivo</i>Christopher P Tinworth, Justyna Wojno-Picon, Michael Adam, et al.
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging|June 21, 2023
Structural and Functional Brain Patterns Predict Formal Thought Disorder's Severity and Its Persistence in Recent-Onset Psychosis: Results From the PRONIA StudyMadalina-Octavia Buciuman, Oemer Faruk Oeztuerk, David Popovic, et al.
Journal of Medicinal Chemistry|January 16, 2016
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate DerivativesSusan M Westaway, Alex G S Preston, Michael D Barker, et al.
Ebiomedicine|January 1, 2025
Evaluation of intestinal biopsy tissue preservation methods to facilitate large-scale mucosal microbiota researchNicola J Wyatt, Hannah Watson, Gregory R Young, et al.
Nature Chemical Biology|January 27, 2015
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formationHuw D Lewis, John Liddle, Jim E Coote, et al.
EMBO Molecular Medicine|January 29, 2021
Development of a small molecule that corrects misfolding and increases secretion of Z α<sub>1</sub> -antitrypsinDavid A Lomas, James A Irving, Christopher Arico-Muendel, et al.
The Lancet. Rheumatology|September 1, 2020
COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort studyJessica J Manson, Colin Crooks, Meena Naja, et al.
Nature Communications|September 6, 2023
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancerCorina E Antal, Tae Gyu Oh, Stefan Aigner, et al.
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