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Molecular Psychiatry|April 3, 2023
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTDWei Luan, Amanda L Wright, Heledd Brown-Wright, et al.BMJ Neurology Open|December 26, 2025
Study protocol for a multicentre, randomised, double-blinded, placebo-controlled, multi-arm, multi-stage, trial of SpironolacTone and famciclOovir in the treatment of Progressive Multiple Sclerosis to prevent disability progression: the STOP-MS trialKayla Ward, Vivien Li, Sudarshini Ramanathan, et al.Nature Communications|February 19, 2024
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegenerationRebecca San Gil, Dana Pascovici, Juliana Venturato, et al.Nature Communications|August 18, 2025
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trialBrittany N Flores, Seungyoon B Yu, Isaac V Cohen, et al.Pageof 1