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Open Forum Infectious Diseases
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May 13, 2022
Incidence, Etiology, and Environmental Risk Factors of Community-Acquired Pneumonia Requiring Hospitalization in China: A 3-Year, Prospective, Age-Stratified, Multicenter Case-Control Study
Tian Qin, Haijian Zhou, Hongyu Ren, et al.
Journal of Medicinal Chemistry
|
July 18, 2019
Identification of <i>N</i>-Methyl Nicotinamide and <i>N</i>-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)
Ryan Moslin, Yanlei Zhang, Stephen T Wrobleski, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 14, 2023
Structure-activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4' and C6 variations
Zili Xiao, Michael G Yang, Chunjian Liu, et al.
Science Translational Medicine
|
July 26, 2019
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain
James R Burke, Lihong Cheng, Kathleen M Gillooly, et al.
ACS Medicinal Chemistry Letters
|
March 21, 2019
Identification of Imidazo[1,2-<i>b</i>]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors
Chunjian Liu, James Lin, Ryan Moslin, et al.
Journal of Medicinal Chemistry
|
July 19, 2019
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165
Stephen T Wrobleski, Ryan Moslin, Shuqun Lin, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
Anurag S Srivastava, Soo Ko, Scott H Watterson, et al.
Journal of Diabetes
|
March 12, 2021
Associations between parity, pregnancy loss, and breastfeeding duration and risk of maternal type 2 diabetes: An observational cohort study
Yanan Huo, Lihong Cheng, Chenxiu Wang, et al.
Journal of Medicinal Chemistry
|
March 21, 2019
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)
Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, et al.
Journal of Medicinal Chemistry
|
September 2, 2016
Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers
Scott H Watterson, George V De Lucca, Qing Shi, et al.
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of 10
Search research articles
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Showing results (91-100 of 100) with videos related to
Sort By:
Page
of 10
You have reached the last page of results.
This site can display upto 100 results.
Open Forum Infectious Diseases
|
May 13, 2022
Incidence, Etiology, and Environmental Risk Factors of Community-Acquired Pneumonia Requiring Hospitalization in China: A 3-Year, Prospective, Age-Stratified, Multicenter Case-Control Study
Tian Qin, Haijian Zhou, Hongyu Ren, et al.
Journal of Medicinal Chemistry
|
July 18, 2019
Identification of <i>N</i>-Methyl Nicotinamide and <i>N</i>-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)
Ryan Moslin, Yanlei Zhang, Stephen T Wrobleski, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 14, 2023
Structure-activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4' and C6 variations
Zili Xiao, Michael G Yang, Chunjian Liu, et al.
Science Translational Medicine
|
July 26, 2019
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain
James R Burke, Lihong Cheng, Kathleen M Gillooly, et al.
ACS Medicinal Chemistry Letters
|
March 21, 2019
Identification of Imidazo[1,2-<i>b</i>]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors
Chunjian Liu, James Lin, Ryan Moslin, et al.
Journal of Medicinal Chemistry
|
July 19, 2019
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165
Stephen T Wrobleski, Ryan Moslin, Shuqun Lin, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
Anurag S Srivastava, Soo Ko, Scott H Watterson, et al.
Journal of Diabetes
|
March 12, 2021
Associations between parity, pregnancy loss, and breastfeeding duration and risk of maternal type 2 diabetes: An observational cohort study
Yanan Huo, Lihong Cheng, Chenxiu Wang, et al.
Journal of Medicinal Chemistry
|
March 21, 2019
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)
Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, et al.
Journal of Medicinal Chemistry
|
September 2, 2016
Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers
Scott H Watterson, George V De Lucca, Qing Shi, et al.
Page
of 10