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Plos Biology
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August 26, 2025
MK-8527 is a novel inhibitor of HIV-1 reverse transcriptase translocation with potential for extended-duration dosing
Izzat T Raheem, Vinay Girijavallabhan, Kerry L Fillgrove, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure
Michael T Rudd, John A McCauley, John W Butcher, et al.
Nature
|
September 9, 2021
The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity
Rory N Pruitt, Federica Locci, Friederike Wanke, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2009
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants
Dai-Shi Su, John J Lim, Elizabeth Tinney, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 2010
Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif
Dai-Shi Su, John J Lim, Elizabeth Tinney, et al.
Journal of Medicinal Chemistry
|
February 19, 2010
Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor
John A McCauley, Charles J McIntyre, Michael T Rudd, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 23, 2012
Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers
Michael T Rudd, Charles J McIntyre, Joseph J Romano, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 2, 2012
Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease
Michael T Rudd, John A McCauley, Joseph J Romano, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Alpha-hydroxy amides as a novel class of bradykinin B1 selective antagonists
Michael R Wood, Kathy M Schirripa, June J Kim, et al.
The New England Journal of Medicine
|
March 18, 2011
Fever with thrombocytopenia associated with a novel bunyavirus in China
Xue-Jie Yu, Mi-Fang Liang, Shou-Yin Zhang, et al.
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of 50
Search research articles
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Showing results (481-490 of 491) with videos related to
Sort By:
Page
of 50
Plos Biology
|
August 26, 2025
MK-8527 is a novel inhibitor of HIV-1 reverse transcriptase translocation with potential for extended-duration dosing
Izzat T Raheem, Vinay Girijavallabhan, Kerry L Fillgrove, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure
Michael T Rudd, John A McCauley, John W Butcher, et al.
Nature
|
September 9, 2021
The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity
Rory N Pruitt, Federica Locci, Friederike Wanke, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2009
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants
Dai-Shi Su, John J Lim, Elizabeth Tinney, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 2010
Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif
Dai-Shi Su, John J Lim, Elizabeth Tinney, et al.
Journal of Medicinal Chemistry
|
February 19, 2010
Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor
John A McCauley, Charles J McIntyre, Michael T Rudd, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 23, 2012
Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers
Michael T Rudd, Charles J McIntyre, Joseph J Romano, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 2, 2012
Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease
Michael T Rudd, John A McCauley, Joseph J Romano, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Alpha-hydroxy amides as a novel class of bradykinin B1 selective antagonists
Michael R Wood, Kathy M Schirripa, June J Kim, et al.
The New England Journal of Medicine
|
March 18, 2011
Fever with thrombocytopenia associated with a novel bunyavirus in China
Xue-Jie Yu, Mi-Fang Liang, Shou-Yin Zhang, et al.
Page
of 50