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Basic Research in Cardiology|September 11, 2025
Cardiac sodium-glucose co-transporter 1 (SGLT1) contributes to heart failure in a mouse model of diabetic cardiomyopathyZhao Li, Sydney Freiberg, Meredith L Music, et al.
Journal of Medicinal Chemistry|April 10, 2024
Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted CancersKevin M Cottrell, Kimberly J Briggs, Douglas A Whittington, et al.
Bioorganic & Medicinal Chemistry Letters|May 2, 2025
Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitorScott Throner, Tianshu Feng, Jannik N Andersen, et al.
Molecular Cancer Therapeutics|October 13, 2022
Ubiquitinated PCNA Drives USP1 Synthetic Lethality in CancerAntoine Simoneau, Justin L Engel, Madhavi Bandi, et al.
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