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Science Advances|June 24, 2026
Isoform-specific steric zippers drive aberrant assembly and mislocalization of shortened TDP-43Katie E Copley, Megan M Dykstra, Morgan R Miller, et al.The Journal of Biological Chemistry|December 29, 2019
Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprintingElizabeth A Sweeny, Amber Tariq, Esin Gurpinar, et al.Nature Structural & Molecular Biology|April 22, 2020
Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysisKyle E Lopez, Alexandrea N Rizo, Eric Tse, et al.Journal of Molecular Biology|July 22, 2023
Cryo-EM Structure of the Full-length hnRNPA1 Amyloid FibrilKartikay Sharma, Sambhasan Banerjee, Dilan Savran, et al.Molecular Cell|May 19, 2022
Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separationHui Shen, Amber Yanas, Michael C Owens, et al.Biophysical Journal|April 28, 2019
Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive TranslocasesClarissa L Durie, JiaBei Lin, Nathaniel W Scull, et al.Molecular Cell|February 19, 2022
Poly(ADP-ribose) drives condensation of FUS via a transient interactionKevin Rhine, Morgan Dasovich, Joseph Yoniles, et al.Cell Reports|December 13, 2024
Design principles to tailor Hsp104 therapeuticsJiaBei Lin, Peter J Carman, Craig W Gambogi, et al.Trends in Cell Biology|April 1, 2018
Protein Phase Separation: A New Phase in Cell BiologySteven Boeynaems, Simon Alberti, Nicolas L Fawzi, et al.Biorxiv : the Preprint Server for Biology|May 7, 2024
Design principles to tailor Hsp104 therapeuticsJiaBei Lin, Peter J Carman, Craig W Gambogi, et al.Pageof 19