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Methods in Enzymology|January 22, 2023
Optimized protocols for the characterization of Cas12a activitiesLindsie Martin, Saadi Rostami, Rakhi Rajan
Frontiers in Cellular and Infection Microbiology|February 15, 2021
The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse BiotechnologiesSydney Newsom, Hari Priya Parameshwaran, Lindsie Martin, et al.
Biorxiv : the Preprint Server for Biology|January 20, 2025
Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activationChhandosee Ganguly, Lindsie Martin, Swarmistha Aribam, et al.
Biochemical and Biophysical Research Communications|May 17, 2026
Helicity of the bridge helix of Cas12a regulates on-target DNA cleavage efficiency and off-target cleavage propensityLindsie Martin, Saadi Rostami, Isabelle Schuster, et al.
Nature Communications|January 28, 2026
Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activationChhandosee Ganguly, Swarmistha Devi Aribam, Alberto Monteiro Dos Santos, et al.
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