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ACS Infectious Diseases|July 21, 2020
An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin PolymerizationImran Ullah, Suraksha Gahalawat, Laela M Booshehri, et al.Journal of Medicinal Chemistry|June 23, 2026
Discovery of SMD-6346: A Potent, Selective, and Orally Active SMARCA2 Degrader for Targeting SMARCA4-Deficient Human CancersLingying Leng, Liyue Huang, Wenbin Tu, et al.The Journal of Biological Chemistry|May 15, 2013
Identification of DNMT1 selective antagonists using a novel scintillation proximity assayJessica A Kilgore, Xinlin Du, Lisa Melito, et al.Haematologica|February 24, 2018
A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor supportAmar Desai, Yongyou Zhang, Youngsoo Park, et al.Nature Communications|February 11, 2023
Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing systemWei Huang, Hongyun Li, Janna Kiselar, et al.Antiviral Research|January 3, 2018
A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replicationPriya Luthra, Jue Liang, Colette A Pietzsch, et al.Journal of Medicinal Chemistry|April 5, 2014
Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike propertiesJacinth Naidoo, Hector De Jesus-Cortes, Paula Huntington, et al.Cell Stem Cell|January 29, 2022
In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regenerationYuemeng Jia, Lin Li, Yu-Hsuan Lin, et al.Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation|May 19, 2020
Inhibition of 15-PGDH Protects Mice from Immune-Mediated Bone Marrow FailureJulianne N P Smith, Folashade Otegbeye, Alvin P Jogasuria, et al.Cell|April 6, 2022
A male-derived nonribosomal peptide pheromone controls female schistosome developmentRui Chen, Jipeng Wang, Irina Gradinaru, et al.Pageof 10