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Journal of Medicinal Chemistry|June 12, 2023
Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2')-Orn-NH<sub>2</sub>] at the MC1R, MC3R, MC4R, and MC5R that Mediates an Increased Feeding Response in Mice and a 40-Fold Selective MC1R Antagonist [Ac-DPhe(pI)-DArg-Nal(2')-Arg-NH<sub>2</sub>]Mark D Ericson, Linh T Tran, Sarah S Mathre, et al.Journal of Natural Products|April 1, 2025
Total Synthesis and Pharmacological Evaluation of Phochrodines A-CJacob L Bouchard, Sichen Chang, Srinivasan Krishnan, et al.Assay and Drug Development Technologies|February 17, 2026
Identification of Kir2.1 Inhibitors from a High-Throughput ScreenJacob L Bouchard, Pedro de Andrade Horn, Yu Nishio, et al.Scientific Reports|July 1, 2026
Development of a hemolysis filter system for the selective removal of free hemoglobin, haem and iron from blood envisaged for use in extracorporeal circuitsNoora Naghavi, Lisa Barbaro, Mark Jd Griffiths, et al.ACS Bio & Med Chem Au|April 27, 2023
Discovery of "Molecular Switches" within a Series of mGlu<sub>5</sub> Allosteric Ligands Driven by a "Magic Methyl" Effect Affording Both PAMs and NAMs with <i>In Vivo</i> Activity, Derived from an M<sub>1</sub> PAM ChemotypeLisa Barbaro, Alice L Rodriguez, Ashlyn N Blevins, et al.ACS Pharmacology & Translational Science|April 18, 2024
Discovery of Protease-Activated Receptor 4 (PAR4)-Tethered Ligand Antagonists Using Ultralarge Virtual ScreeningShannon T Smith, Jackson B Cassada, Lukas Von Bredow, et al.Pageof 2