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Bioorganic & Medicinal Chemistry Letters
|
December 27, 2011
Synthesis and structure-activity relationship of 5-pyridazin-3-one phenoxypiperidines as potent, selective histamine H(3) receptor inverse agonists
Ming Tao, Lisa D Aimone, John A Gruner, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 28, 2012
Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists
Allison L Zulli, Lisa D Aimone, Joanne R Mathiasen, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2011
Synthesis and evaluation of pyridone-phenoxypropyl-R-2-methylpyrrolidine analogues as histamine H3 receptor antagonists
Nadine C Becknell, Jacquelyn A Lyons, Lisa D Aimone, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 12, 2014
Discovery of (1R,6S)-5-[4-(1-cyclobutyl-piperidin-4-yloxy)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one (R,S-4a): histamine H(3) receptor inverse agonist demonstrating potent cognitive enhancing and wake promoting activity
Robert L Hudkins, Kurt A Josef, Nadine C Becknell, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 8, 2006
Novel C-3 N-urea, amide, and carbamate dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole analogs as potent TIE-2 and VEGF-R2 dual inhibitors
Nadine C Becknell, Allison L Zulli, Thelma S Angeles, et al.
Neuropharmacology
|
September 25, 2015
3-(1'-Cyclobutylspiro[4H-1,3-benzodioxine-2,4'-piperidine]-6-yl)-5,5-dimethyl-1,4-dihydropyridazin-6-one (CEP-32215), a new wake-promoting histamine H3 antagonist/inverse agonist
Robert L Hudkins, John A Gruner, Rita Raddatz, et al.
European Journal of Medicinal Chemistry
|
April 2, 2015
3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activity
Robert L Hudkins, Nadine C Becknell, Jacquelyn A Lyons, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 28, 2011
Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activity
Reddeppa Reddy Dandu, John A Gruner, Joanne R Mathiasen, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 9, 2011
Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: control of selectivity by a benzyloxy group
Rabindranath Tripathy, Robert J McHugh, Arup K Ghose, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 2, 2012
Wake promoting agents: search for next generation modafinil, lessons learned: part III
Derek Dunn, Greg Hostetler, Mohamed Iqbal, et al.
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Search research articles
Search
Showing results (11-20 of 48) with videos related to
Sort By:
Page
of 5
Bioorganic & Medicinal Chemistry Letters
|
December 27, 2011
Synthesis and structure-activity relationship of 5-pyridazin-3-one phenoxypiperidines as potent, selective histamine H(3) receptor inverse agonists
Ming Tao, Lisa D Aimone, John A Gruner, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 28, 2012
Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists
Allison L Zulli, Lisa D Aimone, Joanne R Mathiasen, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2011
Synthesis and evaluation of pyridone-phenoxypropyl-R-2-methylpyrrolidine analogues as histamine H3 receptor antagonists
Nadine C Becknell, Jacquelyn A Lyons, Lisa D Aimone, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 12, 2014
Discovery of (1R,6S)-5-[4-(1-cyclobutyl-piperidin-4-yloxy)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one (R,S-4a): histamine H(3) receptor inverse agonist demonstrating potent cognitive enhancing and wake promoting activity
Robert L Hudkins, Kurt A Josef, Nadine C Becknell, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 8, 2006
Novel C-3 N-urea, amide, and carbamate dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole analogs as potent TIE-2 and VEGF-R2 dual inhibitors
Nadine C Becknell, Allison L Zulli, Thelma S Angeles, et al.
Neuropharmacology
|
September 25, 2015
3-(1'-Cyclobutylspiro[4H-1,3-benzodioxine-2,4'-piperidine]-6-yl)-5,5-dimethyl-1,4-dihydropyridazin-6-one (CEP-32215), a new wake-promoting histamine H3 antagonist/inverse agonist
Robert L Hudkins, John A Gruner, Rita Raddatz, et al.
European Journal of Medicinal Chemistry
|
April 2, 2015
3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activity
Robert L Hudkins, Nadine C Becknell, Jacquelyn A Lyons, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 28, 2011
Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activity
Reddeppa Reddy Dandu, John A Gruner, Joanne R Mathiasen, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 9, 2011
Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: control of selectivity by a benzyloxy group
Rabindranath Tripathy, Robert J McHugh, Arup K Ghose, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 2, 2012
Wake promoting agents: search for next generation modafinil, lessons learned: part III
Derek Dunn, Greg Hostetler, Mohamed Iqbal, et al.
Page
of 5