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Bioorganic & Medicinal Chemistry Letters
|
January 10, 2012
Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test
Rabindranath Tripathy, Robert J McHugh, Edward R Bacon, et al.
Journal of Medicinal Chemistry
|
May 19, 2012
A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779
Benjamin J Dugan, Diane E Gingrich, Eugen F Mesaros, et al.
Journal of Medicinal Chemistry
|
August 22, 2008
Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models
Robert L Hudkins, James L Diebold, Ming Tao, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 16, 2011
Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases
Craig A Zificsak, Diane E Gingrich, Henry J Breslin, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 31, 2010
2,4-Diaminopyrimidine inhibitors of c-Met kinase bearing benzoxazepine anilines
Craig A Zificsak, Jay P Theroff, Lisa D Aimone, et al.
Journal of Medicinal Chemistry
|
December 7, 2011
Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f][1,2,4]triazines: identification of orally bioavailable, efficacious ALK inhibitors
Eugen F Mesaros, Tho V Thieu, Gregory J Wells, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2011
Novel brain penetrant benzofuropiperidine 5-HT₆ receptor antagonists
Babu G Sundar, Thomas R Bailey, Derek D Dunn, et al.
Journal of Medicinal Chemistry
|
August 17, 2016
Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK)
Gregory R Ott, Mangeng Cheng, Keith S Learn, et al.
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Showing results (41-50 of 48) with videos related to
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This site can display upto 48 results.
Bioorganic & Medicinal Chemistry Letters
|
January 10, 2012
Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test
Rabindranath Tripathy, Robert J McHugh, Edward R Bacon, et al.
Journal of Medicinal Chemistry
|
May 19, 2012
A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779
Benjamin J Dugan, Diane E Gingrich, Eugen F Mesaros, et al.
Journal of Medicinal Chemistry
|
August 22, 2008
Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models
Robert L Hudkins, James L Diebold, Ming Tao, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 16, 2011
Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases
Craig A Zificsak, Diane E Gingrich, Henry J Breslin, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 31, 2010
2,4-Diaminopyrimidine inhibitors of c-Met kinase bearing benzoxazepine anilines
Craig A Zificsak, Jay P Theroff, Lisa D Aimone, et al.
Journal of Medicinal Chemistry
|
December 7, 2011
Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f][1,2,4]triazines: identification of orally bioavailable, efficacious ALK inhibitors
Eugen F Mesaros, Tho V Thieu, Gregory J Wells, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2011
Novel brain penetrant benzofuropiperidine 5-HT₆ receptor antagonists
Babu G Sundar, Thomas R Bailey, Derek D Dunn, et al.
Journal of Medicinal Chemistry
|
August 17, 2016
Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK)
Gregory R Ott, Mangeng Cheng, Keith S Learn, et al.
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of 5