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Bioorganic & Medicinal Chemistry Letters
|
July 12, 2013
Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507
David A Scott, Les A Dakin, Kevin Daly, et al.
Journal of Medicinal Chemistry
|
October 18, 2019
Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors Targeting MyD88<sup>L265P</sup> Mutant Diffuse Large B Cell Lymphoma
Sébastien L Degorce, Rana Anjum, Andrew Bloecher, et al.
Blood
|
December 1, 2018
Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas
Raphael Koch, Amanda L Christie, Jennifer L Crombie, et al.
The Journal of Clinical Investigation
|
December 1, 2021
Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model
Melody Li, Nikola Jancovski, Paymaan Jafar-Nejad, et al.
Science Translational Medicine
|
January 27, 2012
Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers
Ryohei Katayama, Alice T Shaw, Tahsin M Khan, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 9, 2019
AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells
Justin Cidado, Scott Boiko, Theresa Proia, et al.
Nature Communications
|
November 16, 2019
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
Matthew J Sale, Emma Minihane, Noel R Monks, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 23, 2008
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity
Paul D Lyne, Brian Aquila, Donald J Cook, et al.
NPJ Precision Oncology
|
December 27, 2022
The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells
Steven W Criscione, Matthew J Martin, Derek B Oien, et al.
Journal of Medicinal Chemistry
|
February 13, 2013
Discovery and optimization of a novel series of potent mutant B-Raf(V600E) selective kinase inhibitors
Melissa M Vasbinder, Brian Aquila, Martin Augustin, et al.
Page
of 5
Search research articles
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Showing results (21-30 of 41) with videos related to
Sort By:
Page
of 5
Bioorganic & Medicinal Chemistry Letters
|
July 12, 2013
Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507
David A Scott, Les A Dakin, Kevin Daly, et al.
Journal of Medicinal Chemistry
|
October 18, 2019
Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors Targeting MyD88<sup>L265P</sup> Mutant Diffuse Large B Cell Lymphoma
Sébastien L Degorce, Rana Anjum, Andrew Bloecher, et al.
Blood
|
December 1, 2018
Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas
Raphael Koch, Amanda L Christie, Jennifer L Crombie, et al.
The Journal of Clinical Investigation
|
December 1, 2021
Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model
Melody Li, Nikola Jancovski, Paymaan Jafar-Nejad, et al.
Science Translational Medicine
|
January 27, 2012
Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers
Ryohei Katayama, Alice T Shaw, Tahsin M Khan, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 9, 2019
AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells
Justin Cidado, Scott Boiko, Theresa Proia, et al.
Nature Communications
|
November 16, 2019
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
Matthew J Sale, Emma Minihane, Noel R Monks, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 23, 2008
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity
Paul D Lyne, Brian Aquila, Donald J Cook, et al.
NPJ Precision Oncology
|
December 27, 2022
The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells
Steven W Criscione, Matthew J Martin, Derek B Oien, et al.
Journal of Medicinal Chemistry
|
February 13, 2013
Discovery and optimization of a novel series of potent mutant B-Raf(V600E) selective kinase inhibitors
Melissa M Vasbinder, Brian Aquila, Martin Augustin, et al.
Page
of 5