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European Journal of Pharmacology|October 2, 2002
PSAB-OFP, a selective alpha 7 nicotinic receptor agonist, is also a potent agonist of the 5-HT3 receptorLisa M Broad, Catherine Felthouse, Ruud Zwart, et al.
Clinical Pharmacology and Therapeutics|August 10, 2023
TRPA1 Antagonist LY3526318 Inhibits the Cinnamaldehyde-Evoked Dermal Blood Flow Increase: Translational Proof of PharmacologyDorien Bamps, Anthony James Blockeel, Erwin Dreesen, et al.
British Journal of Pharmacology|October 3, 2018
Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptorsLisa M Broad, Helen E Sanger, Adrian J Mogg, et al.
Cephalalgia : an International Journal of Headache|August 21, 2025
Preclinical and clinical evaluation of LY3451838, a PACAP-neutralizing monoclonal antibody, in randomized, double-blind, placebo-controlled phase 1 and phase 2 studies involving healthy adults and adults with treatment-resistant migraineMichael P Johnson, Judith Krikke-Workel, Chetan N Patel, et al.
The Journal of Biological Chemistry|January 31, 2016
An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and MemoryAdrian J Butcher, Sophie J Bradley, Rudi Prihandoko, et al.
Psychopharmacology|January 17, 2014
Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neuronsJeffrey L Dage, Ellen M Colvin, Antoine Fouillet, et al.
Molecular Pharmacology|April 27, 2018
Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial OutcomesSophie J Bradley, Colin Molloy, Christoffer Bundgaard, et al.
European Journal of Pharmacology|October 7, 2004
Stable expression and characterisation of a human alpha 7 nicotinic subunit chimera: a tool for functional high-throughput screeningPeter J Craig, Suchira Bose, Ruud Zwart, et al.
Neuropharmacology|August 14, 2012
In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the ratGary Gilmour, Lisa M Broad, Keith A Wafford, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 13, 2018
In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J Mogg, Thomas Eessalu, Megan Johnson, et al.
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