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International Journal of Oncology
|
May 14, 2016
The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells
Seema-Maria Nathwani, Lisa M Greene, Stefania Butini, et al.
European Journal of Medicinal Chemistry
|
March 5, 2013
Synthesis and biochemical activities of antiproliferative amino acid and phosphate derivatives of microtubule-disrupting β-lactam combretastatins
Niamh M O'Boyle, Lisa M Greene, Niall O Keely, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 15, 2004
Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL
Margaret M Mc Gee, Lisa M Greene, Susan Ledwidge, et al.
Oncology Reports
|
December 13, 2012
Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro
Seema-Maria Nathwani, Linda Hughes, Lisa M Greene, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry
|
March 13, 2010
Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects
Irene Barrett, Miriam Carr, Niamh O'Boyle, et al.
Bioorganic & Medicinal Chemistry
|
March 15, 2011
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
Niamh M O'Boyle, Lisa M Greene, Orla Bergin, et al.
Oncology Reports
|
April 9, 2013
Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer
Lisa M Greene, Shu Wang, Niamh M O'Boyle, et al.
Investigational New Drugs
|
February 18, 2016
The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15
Paula Kinsella, Lisa M Greene, Sandra A Bright, et al.
Journal of Medicinal Chemistry
|
November 18, 2010
Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents
Niamh M O'Boyle, Miriam Carr, Lisa M Greene, et al.
European Journal of Medicinal Chemistry
|
March 4, 2017
β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells
Azizah M Malebari, Lisa M Greene, Seema M Nathwani, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 28) with videos related to
Sort By:
Page
of 3
International Journal of Oncology
|
May 14, 2016
The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells
Seema-Maria Nathwani, Lisa M Greene, Stefania Butini, et al.
European Journal of Medicinal Chemistry
|
March 5, 2013
Synthesis and biochemical activities of antiproliferative amino acid and phosphate derivatives of microtubule-disrupting β-lactam combretastatins
Niamh M O'Boyle, Lisa M Greene, Niall O Keely, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 15, 2004
Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL
Margaret M Mc Gee, Lisa M Greene, Susan Ledwidge, et al.
Oncology Reports
|
December 13, 2012
Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro
Seema-Maria Nathwani, Linda Hughes, Lisa M Greene, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry
|
March 13, 2010
Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects
Irene Barrett, Miriam Carr, Niamh O'Boyle, et al.
Bioorganic & Medicinal Chemistry
|
March 15, 2011
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
Niamh M O'Boyle, Lisa M Greene, Orla Bergin, et al.
Oncology Reports
|
April 9, 2013
Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer
Lisa M Greene, Shu Wang, Niamh M O'Boyle, et al.
Investigational New Drugs
|
February 18, 2016
The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15
Paula Kinsella, Lisa M Greene, Sandra A Bright, et al.
Journal of Medicinal Chemistry
|
November 18, 2010
Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents
Niamh M O'Boyle, Miriam Carr, Lisa M Greene, et al.
European Journal of Medicinal Chemistry
|
March 4, 2017
β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells
Azizah M Malebari, Lisa M Greene, Seema M Nathwani, et al.
Page
of 3