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Bioorganic & Medicinal Chemistry Letters|February 17, 2006
4-Amino derivatives of the Hsp90 inhibitor CCT018159Xavier Barril, Mandy C Beswick, Adam Collier, et al.Science Signaling|June 23, 2016
MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesisChristophe Cataisson, Aleksandra M Michalowski, Kelly Shibuya, et al.Chemistry & Biology|June 26, 2004
Structure-activity relationships in purine-based inhibitor binding to HSP90 isoformsLisa Wright, Xavier Barril, Brian Dymock, et al.Critical Care Medicine|April 14, 2023
Implementation of Video Laryngoscope-Assisted Coaching Reduces Adverse Tracheal Intubation-Associated Events in the PICUJohn Giuliano, Ashwin Krishna, Natalie Napolitano, et al.Bioorganic & Medicinal Chemistry|September 29, 2012
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimizationNicholas G M Davies, Helen Browne, Ben Davis, et al.Molecular Cancer Therapeutics|April 14, 2007
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analoguesSwee Y Sharp, Chrisostomos Prodromou, Kathy Boxall, et al.Journal of Medicinal Chemistry|July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperonePaul A Brough, Xavier Barril, Jenifer Borgognoni, et al.Cancer Research|April 17, 2008
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasisSuzanne A Eccles, Andy Massey, Florence I Raynaud, et al.Journal of Medicinal Chemistry|November 21, 2007
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancerPaul A Brough, Wynne Aherne, Xavier Barril, et al.Pageof 18