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Assay and Drug Development Technologies
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May 13, 2011
Development of a cyclic adenosine monophosphate assay for Gi-coupled G protein-coupled receptors by utilizing the endogenous calcitonin activity in Chinese hamster ovary cells
Yuren Wang, Yan Kong, Gan Ju Shei, et al.
Journal of Medicinal Chemistry
|
March 21, 2003
Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties
Timothy F Herpin, Guixue Yu, Kenneth E Carlson, et al.
ACS Combinatorial Science
|
February 21, 2012
Solid phase synthesis of 1,5-diarylpyrazole-4-carboxamides: discovery of antagonists of the CB-1 receptor
Annapurna Pendri, Dharmpal S Dodd, Jing Chen, et al.
European Journal of Pharmacology
|
November 4, 2010
Cannabinoid CB(1) receptor ligand binding and function examined through mutagenesis studies of F200 and S383
Doree F Sitkoff, Ning Lee, Bruce A Ellsworth, et al.
Iscience
|
June 30, 2021
Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation
Danna M Breen, Srinath Jagarlapudi, Anita Patel, et al.
Journal of Leukocyte Biology
|
August 5, 2006
A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice
Liya Kang, Kim W McIntyre, Kathleen M Gillooly, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 22, 2007
Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series
Bruce A Ellsworth, Ying Wang, Yeheng Zhu, et al.
Scientific Reports
|
April 27, 2021
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation
Ella Fung, Liya Kang, Diana Sapashnik, et al.
Nature Communications
|
July 4, 2023
Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity
Stephen E Flaherty, Olivier Bezy, Wei Zheng, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
July 24, 2012
Cannabinoid receptor antagonist-induced striated muscle toxicity and ethylmalonic-adipic aciduria in beagle dogs
Lindsay Tomlinson, Mark A Tirmenstein, Evan B Janovitz, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 11) with videos related to
Sort By:
Page
of 2
Assay and Drug Development Technologies
|
May 13, 2011
Development of a cyclic adenosine monophosphate assay for Gi-coupled G protein-coupled receptors by utilizing the endogenous calcitonin activity in Chinese hamster ovary cells
Yuren Wang, Yan Kong, Gan Ju Shei, et al.
Journal of Medicinal Chemistry
|
March 21, 2003
Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties
Timothy F Herpin, Guixue Yu, Kenneth E Carlson, et al.
ACS Combinatorial Science
|
February 21, 2012
Solid phase synthesis of 1,5-diarylpyrazole-4-carboxamides: discovery of antagonists of the CB-1 receptor
Annapurna Pendri, Dharmpal S Dodd, Jing Chen, et al.
European Journal of Pharmacology
|
November 4, 2010
Cannabinoid CB(1) receptor ligand binding and function examined through mutagenesis studies of F200 and S383
Doree F Sitkoff, Ning Lee, Bruce A Ellsworth, et al.
Iscience
|
June 30, 2021
Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation
Danna M Breen, Srinath Jagarlapudi, Anita Patel, et al.
Journal of Leukocyte Biology
|
August 5, 2006
A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice
Liya Kang, Kim W McIntyre, Kathleen M Gillooly, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 22, 2007
Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series
Bruce A Ellsworth, Ying Wang, Yeheng Zhu, et al.
Scientific Reports
|
April 27, 2021
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation
Ella Fung, Liya Kang, Diana Sapashnik, et al.
Nature Communications
|
July 4, 2023
Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity
Stephen E Flaherty, Olivier Bezy, Wei Zheng, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
July 24, 2012
Cannabinoid receptor antagonist-induced striated muscle toxicity and ethylmalonic-adipic aciduria in beagle dogs
Lindsay Tomlinson, Mark A Tirmenstein, Evan B Janovitz, et al.
Page
of 2