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Chemistry & Biology|January 25, 2008
Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosisNwakaso N Umejiego, Deviprasad Gollapalli, Lisa Sharling, et al.
Journal of Medicinal Chemistry|October 26, 2007
Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analoguesLiqiang Chen, Guangyao Gao, Krzysztof Felczak, et al.
The Journal of Biological Chemistry|March 17, 2010
Prodrug activation by Cryptosporidium thymidine kinaseXin E Sun, Lisa Sharling, Mani Muthalagi, et al.
The Journal of Biological Chemistry|January 10, 2015
A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivityMagdalena Makowska-Grzyska, Youngchang Kim, Natalia Maltseva, et al.
Chemistry & Biology|February 18, 2014
Arginyltransferase ATE1 catalyzes midchain arginylation of proteins at side chain carboxylates in vivoJunling Wang, Xuemei Han, Catherine C L Wong, et al.
Bioorganic & Medicinal Chemistry Letters|May 17, 2023
Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibitionSeungheon Lee, Melissa S Love, Ramkumar Modukuri, et al.
Antimicrobial Agents and Chemotherapy|December 25, 2013
Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosisSuresh Kumar Gorla, Nina N McNair, Guangyi Yang, et al.
Nature Chemical Biology|November 1, 2011
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymesGregory C Patton, Pål Stenmark, Deviprasad R Gollapalli, et al.
Journal of Medicinal Chemistry|May 15, 2013
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenaseSuresh Kumar Gorla, Mandapati Kavitha, Minjia Zhang, et al.
Journal of Medicinal Chemistry|December 5, 2014
Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) inhibitorsZhuming Sun, Jihan Khan, Magdalena Makowska-Grzyska, et al.
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