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Npj Antimicrobials and Resistance|January 22, 2025
Intradiscal pharmacokinetics of oral antibiotics to treat Chronic Lower Back PainLloyd G Czaplewski, Marcus Zeitlinger, Joseph F StandingJournal of Orthopaedic Surgery and Research|May 11, 2023
Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disabilityLloyd G Czaplewski, Otis Rimmer, Duncan McHale, et al.Molecular Microbiology|February 1, 2011
Multiple effects of benzamide antibiotics on FtsZ functionDavid W Adams, Ling Juan Wu, Lloyd G Czaplewski, et al.The Spine Journal : Official Journal of the North American Spine Society|February 21, 2021
Chronic low back pain, bacterial infection and treatment with antibioticsChristopher J Gilligan, Steven P Cohen, Vincent A Fischetti, et al.European Journal of Medicinal Chemistry|August 20, 2014
Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activityIan A Yule, Lloyd G Czaplewski, Stephanie Pommier, et al.JOR Spine|November 15, 2024
Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administrationGraham Hagger, Sarah Guest, Stephen Birchall, et al.Eclinicalmedicine|March 2, 2026
Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trialMichael R Lassen, Matthew Scarborough, Nigel Gilchrist, et al.Eclinicalmedicine|March 20, 2026
Corrigendum to 'Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial' eClinicalMedicine 2026; 92: 103764Michael R Lassen, Matthew Scarborough, Nigel Gilchrist, et al.Antimicrobial Agents and Chemotherapy|November 2, 2012
An improved small-molecule inhibitor of FtsZ with superior in vitro potency, drug-like properties, and in vivo efficacyNeil R Stokes, Nicola Baker, James M Bennett, et al.The Journal of Biological Chemistry|September 22, 2005
Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assayNeil R Stokes, Jörg Sievers, Stephanie Barker, et al.Pageof 2