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Nature
|
November 15, 2013
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors
David J Lloyd, David J St Jean, Robert J M Kurzeja, et al.
Journal of Medicinal Chemistry
|
November 10, 2015
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational Constraint
Lewis D Pennington, Michael D Bartberger, Michael D Croghan, et al.
Journal of Medicinal Chemistry
|
May 3, 2012
Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
August 5, 2021
[<sup>11</sup>C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
Longbin Liu, Peter D Johnson, Michael E Prime, et al.
Journal of Medicinal Chemistry
|
December 22, 2022
Design and Evaluation of [<sup>18</sup>F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates
Longbin Liu, Peter D Johnson, Michael E Prime, et al.
Journal of Medicinal Chemistry
|
August 18, 2012
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
July 7, 2025
Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates
Longbin Liu, Peter D Johnson, Matthew R Mills, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
Journal of Medicinal Chemistry
|
September 15, 2023
Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease
Longbin Liu, Karine Malagu, Alan F Haughan, et al.
Journal of Medicinal Chemistry
|
July 15, 2020
Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand
Longbin Liu, Michael E Prime, Matt R Lee, et al.
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Search research articles
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Showing results (51-60 of 60) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 60 results.
Nature
|
November 15, 2013
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors
David J Lloyd, David J St Jean, Robert J M Kurzeja, et al.
Journal of Medicinal Chemistry
|
November 10, 2015
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational Constraint
Lewis D Pennington, Michael D Bartberger, Michael D Croghan, et al.
Journal of Medicinal Chemistry
|
May 3, 2012
Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
August 5, 2021
[<sup>11</sup>C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
Longbin Liu, Peter D Johnson, Michael E Prime, et al.
Journal of Medicinal Chemistry
|
December 22, 2022
Design and Evaluation of [<sup>18</sup>F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates
Longbin Liu, Peter D Johnson, Michael E Prime, et al.
Journal of Medicinal Chemistry
|
August 18, 2012
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
July 7, 2025
Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates
Longbin Liu, Peter D Johnson, Matthew R Mills, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
Journal of Medicinal Chemistry
|
September 15, 2023
Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease
Longbin Liu, Karine Malagu, Alan F Haughan, et al.
Journal of Medicinal Chemistry
|
July 15, 2020
Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand
Longbin Liu, Michael E Prime, Matt R Lee, et al.
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