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The Journal of Allergy and Clinical Immunology
|
May 22, 2024
IL-4-STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock
James Krempski, Amnah Yamani, Lakshmi Narasimha Rao Thota, et al.
Journal of Medicinal Chemistry
|
March 25, 2017
Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression
Bing Zhou, Jiantao Hu, Fuming Xu, et al.
Molecular Cancer Therapeutics
|
March 5, 2011
Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment
Jianfeng Lu, Donna McEachern, Haiying Sun, et al.
Journal of Medicinal Chemistry
|
March 13, 2024
Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression
Zhixiang Chen, Mi Wang, Dimin Wu, et al.
Journal of Medicinal Chemistry
|
May 3, 2017
Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor
Yujun Zhao, Longchuan Bai, Liu Liu, et al.
Journal of Medicinal Chemistry
|
March 26, 2024
Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer
Zhixiang Chen, Mi Wang, Dimin Wu, et al.
Journal of Medicinal Chemistry
|
September 23, 2024
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
Atsunori Kaneshige, Yiqing Yang, Longchuan Bai, et al.
Journal of Medicinal Chemistry
|
August 22, 2025
Discovery of a Novel Series of <i>iso</i>-Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders
Xuqing Zhang, Harshil Dhruv, Qiaolin Deng, et al.
Nature Chemical Biology
|
February 2, 2023
A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo
Atsunori Kaneshige, Longchuan Bai, Mi Wang, et al.
Journal of Medicinal Chemistry
|
November 7, 2024
Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
Renqi Xu, Haibin Zhou, Longchuan Bai, et al.
Page
of 7
Search research articles
Search
Showing results (41-50 of 67) with videos related to
Sort By:
Page
of 7
The Journal of Allergy and Clinical Immunology
|
May 22, 2024
IL-4-STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock
James Krempski, Amnah Yamani, Lakshmi Narasimha Rao Thota, et al.
Journal of Medicinal Chemistry
|
March 25, 2017
Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression
Bing Zhou, Jiantao Hu, Fuming Xu, et al.
Molecular Cancer Therapeutics
|
March 5, 2011
Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment
Jianfeng Lu, Donna McEachern, Haiying Sun, et al.
Journal of Medicinal Chemistry
|
March 13, 2024
Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression
Zhixiang Chen, Mi Wang, Dimin Wu, et al.
Journal of Medicinal Chemistry
|
May 3, 2017
Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor
Yujun Zhao, Longchuan Bai, Liu Liu, et al.
Journal of Medicinal Chemistry
|
March 26, 2024
Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer
Zhixiang Chen, Mi Wang, Dimin Wu, et al.
Journal of Medicinal Chemistry
|
September 23, 2024
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
Atsunori Kaneshige, Yiqing Yang, Longchuan Bai, et al.
Journal of Medicinal Chemistry
|
August 22, 2025
Discovery of a Novel Series of <i>iso</i>-Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders
Xuqing Zhang, Harshil Dhruv, Qiaolin Deng, et al.
Nature Chemical Biology
|
February 2, 2023
A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo
Atsunori Kaneshige, Longchuan Bai, Mi Wang, et al.
Journal of Medicinal Chemistry
|
November 7, 2024
Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
Renqi Xu, Haibin Zhou, Longchuan Bai, et al.
Page
of 7