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American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons|August 28, 2022
IL-2 receptor engineering enhances regulatory T cell function suppressed by calcineurin inhibitorToshihito Hirai, Po-Yu Lin, Teresa L Ramos, et al.Science Translational Medicine|December 22, 2021
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemiaQian Zhang, Morgan E Hresko, Lora K Picton, et al.Cell|March 24, 2022
Facile discovery of surrogate cytokine agonistsMichelle Yen, Junming Ren, Qingxiang Liu, et al.Cell|August 26, 2023
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesisNaotaka Tsutsumi, Zahra Masoumi, Sophie C James, et al.The Journal of Clinical Investigation|April 15, 2021
Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation toleranceToshihito Hirai, Teresa L Ramos, Po-Yu Lin, et al.Elife|May 18, 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonistCaleb R Glassman, Leon Su, Sonia S Majri-Morrison, et al.Nature|October 22, 2020
Immune receptor inhibition through enforced phosphatase recruitmentRicardo A Fernandes, Leon Su, Yoko Nishiga, et al.Developmental Cell|March 29, 2017
The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen SpeciesEvan A Bordt, Pascaline Clerc, Brian A Roelofs, et al.Blood|December 23, 2022
Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivoTeresa L Ramos, Sara Bolivar-Wagers, Sujeong Jin, et al.Nature|June 8, 2022
Potentiating adoptive cell therapy using synthetic IL-9 receptorsAnusha Kalbasi, Mikko Siurala, Leon L Su, et al.Pageof 3