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Neurobiology of Disease|February 7, 2024
Casein kinase 1 inhibitor avoids TDP-43 pathology propagation in a patient-derived cellular model of amyotrophic lateral sclerosisEva P Cuevas, Loreto Martinez-Gonzalez, Clara Gordillo, et al.Colloids and Surfaces. B, Biointerfaces|May 20, 2026
Nanotechnology-based encapsulation of neflamapimod: A new therapeutic strategy for lewy body dementiaMaria Paz García-Simarro, Nuria Genicio, Manuel Bañobre-López, et al.ACS Chemical Neuroscience|July 15, 2020
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's DiseaseRita Maria Concetta Di Martino, Letizia Pruccoli, Alessandra Bisi, et al.European Journal of Medicinal Chemistry|November 3, 2020
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosisElisa Rojas-Prats, Loreto Martinez-Gonzalez, Claudia Gonzalo-Consuegra, et al.Journal of Medicinal Chemistry|January 8, 2025
Modulation of Mitochondria-Endoplasmic Reticulum Contacts (MERCs) by Small Molecules as a New Strategy for Restoring Lipid Metabolism in an Amyotrophic Lateral Sclerosis ModelMikel Etxebeste-Mitxeltorena, Hector Flores-Romero, Sandra Ramos-Inza, et al.Neuropharmacology|December 13, 2025
Assessment of the therapeutic effect of IGS2.7, a CK1δ protein kinase inhibitor, in combination with riluzole for the treatment of ALS-associated TDP-43 proteinopathyMarta Gomez-Almeria, Loreto Martinez-Gonzalez, Ana Teresa Matos, et al.Journal of Medicinal Chemistry|April 8, 2025
Structure-Based Discovery Targeting GSK-3α Reveals Potent Nanomolar Selective 4-Phenyl-1H-benzofuro[3,2-b]pyrazolo[4,3-e]pyridine Inhibitor with Promising Glioblastoma and CNS-Active Potential in Cellular ModelsThomas D Emmerich, Eleanor J Taylor-Chilton, Elena Caballero, et al.Journal of Medicinal Chemistry|August 7, 2018
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation InhibitorsAnnachiara Gandini, Manuela Bartolini, Daniele Tedesco, et al.ACS Chemical Neuroscience|August 6, 2025
Design, Synthesis and Biological Evaluation of Chromeno[3,4-b]xanthones as Multifunctional Agents for Alzheimer's DiseaseDaniela Malafaia, Natércia F Brás, Anna Sampietro, et al.Pageof 2