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Bioorganic & Medicinal Chemistry Letters|November 17, 2010
Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1Lawrence R Marcin, Mendi A Higgins, F Christopher Zusi, et al.
Bioorganic & Medicinal Chemistry Letters|October 7, 2011
Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitorsLorin A Thompson, Jianliang Shi, Carl P Decicco, et al.
ACS Medicinal Chemistry Letters|March 21, 2019
Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481Kenneth M Boy, Jason M Guernon, Dmitry S Zuev, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 19, 2016
Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human SubjectsJeremy H Toyn, Kenneth M Boy, Joseph Raybon, et al.
Archives of Biochemistry and Biophysics|February 8, 2003
Comparative studies of active site-ligand interactions among various recombinant constructs of human beta-amyloid precursor protein cleaving enzymeLisa M Kopcho, Jianhong Ma, Jovita Marcinkeviciene, et al.
International Journal of Alzheimer'S Disease|August 7, 2014
Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780Jeremy H Toyn, Lorin A Thompson, Kimberley A Lentz, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 29, 2017
Preclinical Characterization of (<i>R</i>)-3-((3<i>S</i>,4<i>S</i>)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate <i>N</i>-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive DisorderLinda J Bristow, Jyoti Gulia, Michael R Weed, et al.
ACS Medicinal Chemistry Letters|May 26, 2018
BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive DisorderLawrence R Marcin, Jayakumar Warrier, Srinivasan Thangathirupathy, et al.
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