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Journal of Molecular and Cellular Cardiology Plus|January 13, 2025
Transcriptomics reveal stretched human pluripotent stem cell-derived cardiomyocytes as an advantageous hypertrophy modelLotta Pohjolainen, Heikki Ruskoaho, Virpi Talman
Frontiers in Cardiovascular Medicine|June 7, 2023
Genome-wide profiling of miRNA-gene regulatory networks in mouse postnatal heart development-implications for cardiac regenerationUmesh Chaudhari, Lotta Pohjolainen, Heikki Ruskoaho, et al.
Frontiers in Pharmacology|February 15, 2021
Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived CardiomyocytesLotta Pohjolainen, Julia Easton, Reesha Solanki, et al.
Methods in Molecular Biology (Clifton, N.J.)|March 23, 2021
Application of Human Induced Pluripotent Stem Cell Technology for Cardiovascular Regenerative PharmacologyQasim A Majid, Barbara Orsolits, Lotta Pohjolainen, et al.
Journal of the American Heart Association|February 8, 2025
Melanocortin 1 Receptor Regulates Pathological and Physiological Cardiac RemodelingAnni Suominen, Aino Suni, Saku Ruohonen, et al.
Journal of Medicinal Chemistry|September 1, 2017
Discovery of Small Molecules Targeting the Synergy of Cardiac Transcription Factors GATA4 and NKX2-5Mika J Välimäki, Marja A Tölli, Sini M Kinnunen, et al.
The Journal of Physiology|November 11, 2021
Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell-derived cardiomyocytesEline Huethorst, Peter Mortensen, Radostin D Simitev, et al.
Stem Cell Research & Therapy|January 3, 2024
Switching of hypertrophic signalling towards enhanced cardiomyocyte identity and maturity by a GATA4-targeted compoundLotta Pohjolainen, Sini M Kinnunen, Samuli Auno, et al.
Archives of Toxicology|July 11, 2018
Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compoundsS Tuuli Karhu, Mika J Välimäki, Mikael Jumppanen, et al.
EMBO Reports|March 7, 2024
α-Melanocyte-stimulating hormone alleviates pathological cardiac remodeling via melanocortin 5 receptorAnni Suominen, Guillem Saldo Rubio, Saku Ruohonen, et al.
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