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Cancer Discovery|March 1, 2024
A Highly Anticipated Selective Therapeutic Agent against CDK2: INX-315Lotte P Watts, Sabrina L SpencerScience Signaling|November 25, 2025
p16 expression confers sensitivity to CDK2 inhibitors in cyclin E1-driven ovarian cancersChance C Sine, Lotte P Watts, Brianna Fernandez, et al.Elife|November 3, 2020
The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stressLotte P Watts, Toyoaki Natsume, Yuichiro Saito, et al.Nature Communications|July 2, 2025
The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stressQianqian Dong, Matthew Day, Yuichiro Saito, et al.Cell|June 2, 2023
Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticityMansi Arora, Justin Moser, Timothy E Hoffman, et al.Biorxiv : the Preprint Server for Biology|January 20, 2025
Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3'-endsOlivia Luyties, Lynn Sanford, Jessica Rodino, et al.Cell Reports|June 26, 2025
Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3' endsOlivia Luyties, Lynn Sanford, Jessica Rodino, et al.Science (New York, N.Y.)|April 23, 2021
Replication timing maintains the global epigenetic state in human cellsKyle N Klein, Peiyao A Zhao, Xiaowen Lyu, et al.Science Advances|February 28, 2025
TFIIH kinase CDK7 drives cell proliferation through a common core transcription factor networkTaylor Jones, Junjie Feng, Olivia Luyties, et al.Pageof 1